Actively Recruiting

Phase 1
Phase 2
Age: 19Years +
All Genders
NCT06593093

A Bundled Intervention

Led by University of Alabama at Birmingham · Updated on 2026-02-23

190

Participants Needed

1

Research Sites

302 weeks

Total Duration

On this page

Sponsors

U

University of Alabama at Birmingham

Lead Sponsor

N

National Institute on Drug Abuse (NIDA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Opioid overdose deaths have reached historically high records in the United States and are particularly concentrated among patients after emergency department (ED) discharge. Evidence-based treatment modules to reduce repeat opioid overdose and mortality are lacking in this patient population. A bundled intervention is proposed, including telehealth, peer support specialist, buprenorphine, and linkage for definitive care, that is designed to increase treatment uptake in this patient population post-ED discharge, reduce repeat opioid overdoses, and end overdose deaths.

CONDITIONS

Official Title

A Bundled Intervention

Who Can Participate

Age: 19Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Discharged from the emergency department or inpatient settings at the University of Alabama at Birmingham hospital
  • 19 years or older
  • Diagnosed with opioid use disorder and experienced an opioid overdose in the last 12 months
  • Prescribed buprenorphine in the ED and willing to continue it after discharge
  • English speaking
  • Not actively psychotic, suicidal, or cognitively impaired
  • Patients admitted to the hospital from the ED are eligible
Not Eligible

You will not qualify if you...

  • Living in a restricted environment such as prison or jail
  • Currently enrolled in other clinical studies
  • Expected to take prescribed opioids other than buprenorphine for more than three months
  • Known allergy to buprenorphine
  • Critically ill or injured
  • Pregnant females
  • Living outside of Alabama

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UAB

Birmingham, Alabama, United States, 35294

Actively Recruiting

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Research Team

L

Li Li, MD;PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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