Actively Recruiting
Bupivacaine With or Without Dexmedetomidine for Postoperative Pain Relief in Abdominal Surgery
Led by Sheikh Zayed Medical College · Updated on 2025-12-22
80
Participants Needed
1
Research Sites
69 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study investigates the effectiveness of adding dexmedetomidine to bupivacaine for postoperative analgesia in patients undergoing abdominal surgeries. The research compares pain relief in two groups: one receiving a combination of bupivacaine and dexmedetomidine via a transversus abdominis plane (TAP) block, and the other receiving bupivacaine alone. The study aims to evaluate whether dexmedetomidine enhances pain relief, reduces the need for additional pain medication, and impacts sedation and side effects such as hypotension, bradycardia, and nausea. Conducted at Sheikh Zayed Medical College in Rahim Yar Khan, Pakistan, the trial will involve 80 participants and will measure pain using the Visual Analogue Scale (VAS), along with monitoring other vital parameters and complications over 12 hours post-surgery. The primary objective is to determine if the addition of dexmedetomidine provides superior pain control without significantly increasing side effects.
CONDITIONS
Official Title
Bupivacaine With or Without Dexmedetomidine for Postoperative Pain Relief in Abdominal Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 21 to 45 years
- Undergoing elective abdominal surgery such as exploratory laparotomy, ileostomy reversal, laparoscopic or open cholecystectomy, or mesh repair of paraumbilical hernias
- Able to provide informed consent
You will not qualify if you...
- Pregnancy
- Severe allergies to local anesthetics
- Pre-existing chronic pain conditions
- Participation in another clinical trial within the past 30 days
AI-Screening
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Trial Site Locations
Total: 1 location
1
Sheikh Zayed Medical College
Rahim Yar Khan, Punjab Province, Pakistan, 64200
Actively Recruiting
Research Team
R
Rameesha Musharaf, FCPS ANESTHESIA (PGR)
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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