Evaluating Pain Relief Using Bupivacaine With or Without Dexmedetomidine in Ultrasound-Guided TAP Block After Abdominal Surgery

What this Trial Is About

Researchers are evaluating the effect of adding dexmedetomidine to bupivacaine for pain relief after abdominal surgeries. This randomized controlled trial involves 80 patients aged 21 to 45 undergoing elective abdominal surgeries such as exploratory laparotomy, ileostomy reversal, cholecystectomy, or hernia repair. The study compares pain control and side effects between two groups to see if dexmedetomidine improves analgesia without increasing complications. Participants are randomly assigned to one of two groups. One group receives a combination of 0.25% bupivacaine and dexmedetomidine via an ultrasound-guided transversus abdominis plane TAP block at the end of surgery. The other group receives only 0.25% bupivacaine using the same TAP block method. Both groups are monitored for pain relief and other effects over 12 hours post-surgery. During the study, pain levels are measured using the Visual Analogue Scale VAS at multiple time points between 1 and 12 hours after surgery. Researchers also assess sedation using the Ramsay Sedation Scale and monitor vital signs like heart rate and blood pressure. Side effects such as hypotension, bradycardia, and nausea are recorded. Rescue pain medication is given if pain scores exceed 4. Data will be analyzed to determine if dexmedetomidine provides better pain control without increasing side effects.

Bupivacaine With or Without Dexmedetomidine for Postoperative Pain Relief in Abdominal Surgery