Actively Recruiting
Burn Study- Tranexamic Acid Versus Thrombin in Split Thickness Skin Graft
Led by University of Kansas Medical Center · Updated on 2025-10-20
62
Participants Needed
1
Research Sites
124 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Investigators hypothesize that topical tranexamic acid will have better or comparable efficacy to topical thrombin in reducing hematoma formation at the wound base. The purpose of the study is to demonstrate that topical tranexamic acid will be a non-inferior alternative medication to the current standard of care,THROMBIN-JMI® , and at a lower cost to the health system.
CONDITIONS
Official Title
Burn Study- Tranexamic Acid Versus Thrombin in Split Thickness Skin Graft
Who Can Participate
Eligibility Criteria
You may qualify if you...
- English or Spanish speaking
- Flame or scald burn injury
- <=10% total body surface area (TBSA) partial thickness
- <= 5% total body surface area (TBSA) deep partial or full thickness
- Skin graft harvested at 1/12 inch depth, meshed 1:1 or pie crusted if the area is a small functional area
You will not qualify if you...
- >10% total body surface area (TBSA) partial thickness burn
- >5% total body surface area (TBSA )surgical area of burn injury (deep partial or full thickness injury)
- Traumatic or chemical burn mechanism
- Patients on immunosuppression
- Uncontrolled diabetes
- Known diagnosis of peripheral vascular disease or diagnosis at time of injury
- Pregnant women
- Patients with acquired defective color vision
- Patients with subarachnoid hemorrhage
- Patients with active intravascular clotting or known hypersensitivity reactions to tranexamic acid
- Inability to give informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The University of Kansas Health System
Kansas City, Kansas, United States, 66160
Actively Recruiting
Research Team
J
Jessica Reynolds, BSN
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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