Actively Recruiting
Busulfan Sample Collection Study
Led by Saladax Biomedical, Inc. · Updated on 2025-04-03
150
Participants Needed
2
Research Sites
103 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Busulfan (Busulfex®) is an alkylating drug used as a conditioning regimen prior to allogeneic hematopoietic stem cell transplantation. Busulfan has wide inter- and intra-patient pharmacokinetic variability resulting in variable exposure leading to increased risk of toxicities or sub-optimal treatment outcomes. Therapeutic drug monitoring of busulfan using patient plasma samples would benefit clinicians by providing the ability to personalize the dose to achieve a target busulfan exposure.
CONDITIONS
Official Title
Busulfan Sample Collection Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pediatric and adult female or male subjects
- Currently receiving intravenous busulfan treatment for diagnosed malignant hematologic or non-malignant disease
- Adults must be able to understand and provide written informed consent as approved by an Institutional Review Board (IRB)
- Participants under 18 years must provide written assent with legal guardian's IRB-approved consent prior to study procedures
You will not qualify if you...
- Unwilling or unable to follow protocol requirements or to give written informed consent
- Receiving oral busulfan treatment (e.g., Myleran�)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Robert H. Lurie Comprehensive Cancer Center of Northwestern University
Chicago, Illinois, United States, 60611
Actively Recruiting
2
The University of Texas MD Anderson Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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