Actively Recruiting

Phase Not Applicable
Age: 30Years - 75Years
FEMALE
NCT05667532

The C-MERIT Screening Cohort: Contrast-enhanced Mammography for Breast Cancer Screening and Risk Assessment in Women With Dense Breasts

Led by M.D. Anderson Cancer Center · Updated on 2026-01-09

1000

Participants Needed

1

Research Sites

316 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To learn whether a new imaging technology, Contrast-Enhanced Mammography (CEM), compared to standard mammography, can better detect breast cancers in women with dense breasts

CONDITIONS

Official Title

The C-MERIT Screening Cohort: Contrast-enhanced Mammography for Breast Cancer Screening and Risk Assessment in Women With Dense Breasts

Who Can Participate

Age: 30Years - 75Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female patients 30 to 75 years old with dense breasts (ACR BI-RADS categories C and D) undergoing yearly mammography at MDACC
  • Willing to co-enroll or already enrolled in PA17-0584
  • Able and willing to provide informed consent and participate in the study
Not Eligible

You will not qualify if you...

  • New breast symptoms since last mammogram such as nipple discharge, palpable mass, skin dimpling, or focal pain
  • Pregnant or breastfeeding currently or within the past 6 months
  • Personal history of breast cancer including DCIS or invasive breast cancer
  • Treatment for any cancer in the past 5 years except in-situ cervical or non-melanoma skin cancer
  • Breast biopsy within the last 6 months
  • Breast surgery within the last 12 months
  • Breast MRI, MBI, or CEM done within the past 24 months
  • Known allergy to iodine contrast agents
  • History of severe allergic reaction requiring hospitalization or IV placement without prior safe exposure to iodine-based contrast
  • Renal insufficiency as defined by MDACC policy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

M D Anderson Cancer Center

Houston, Texas, United States, 77030

Actively Recruiting

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Research Team

O

Olena Weaver, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SCREENING

Number of Arms

1

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The C-MERIT Screening Cohort: Contrast-enhanced Mammography for Breast Cancer Screening and Risk Assessment in Women With Dense Breasts | DecenTrialz