Actively Recruiting
C-Raven: Pilot Randomized Controlled Trial of Avatar-Delivered Computerized Tobacco Cessation with Community Health Worker Linkage to Lung Cancer Screening in Baltimore City
Led by Johns Hopkins University · Updated on 2026-02-02
30
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
Sponsors
J
Johns Hopkins University
Lead Sponsor
M
Maryland Cigarette Restitution Fund
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating a pilot randomized controlled trial to study a computerized avatar-delivered intervention for tobacco cessation combined with support from community health workers (CHWs) and navigation to lung cancer screening. The study aims to assess recruitment feasibility, participant engagement, completion, and short-term smoking cessation outcomes in a residency clinic setting. Participants will be adults aged 50 and older who currently use tobacco and are considering quitting. The intervention group receives two sessions of computer-delivered counseling via a virtual counselor on a tablet, focusing on tobacco cessation and pharmacotherapy use, including nicotine replacement therapy (patches, gum, or lozenges). CHWs provide training on nicotine therapy use, frequent follow-up calls or video meetings for support, decision-making guidance on lung cancer screening, and assistance with healthcare navigation. The control group waits for six months without intervention and then receives the full computerized intervention and abbreviated CHW support. Participants will be assessed at baseline, 1 month, 3 months, and 6 months with questionnaires on demographics, tobacco use, and readiness to quit. The study measures acceptability and feasibility through module completion and CHW session attendance, as well as uptake of lung cancer screening and nicotine replacement therapy. Follow-up interviews with some participants will gather feedback on the intervention's acceptability. The total follow-up period is six months, with community support continuing during this time.
CONDITIONS
Brief Title
C-Raven, a Virtual Tobacco Cessation Intervention in Residency Clinics
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 50 or older
- Current tobacco user with more than 100 cigarettes smoked in lifetime
- Considering smoking cessation
- Planning to remain in local area for at least 6 months
- English speaking
You will not qualify if you...
- Contraindication to nicotine replacement therapy
- Currently engaged in a formal smoking cessation program
- Major cognitive or psychiatric impairment
- Severe hearing impairment
- Investigator discretion
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants complete informed consent, baseline questionnaires, and initial tobacco use assessments, followed by randomization to intervention or control groups.
1 visit (in-person)
Duration - Up to 12 weeks
Participants in the intervention group receive two computer-delivered tobacco cessation counseling sessions with community health worker support and nicotine replacement therapy over 12 weeks. Control group participants do not receive intervention during this time.
2 in-person sessions plus remote follow-up up to twice weekly for 12 weeks
Duration - 6 months
Participants are assessed at 1 month, 3 months, and 6 months after baseline to evaluate smoking cessation progress, intervention acceptability, and uptake of lung cancer screening.
3 follow-up assessments
Trial Site Locations
Total: 1 location
1
Johns Hopkins University School of Medicine
Baltimore, Maryland, United States, 21205
Actively Recruiting
Research Team
A
Alejandra Ellison-Barnes, MD
H
Heidi Hutton, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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