Actively Recruiting

Phase 4
Age: 50Years +
All Genders
ID07220356

C-Raven: Pilot Randomized Controlled Trial of Avatar-Delivered Computerized Tobacco Cessation with Community Health Worker Linkage to Lung Cancer Screening in Baltimore City

Led by Johns Hopkins University · Updated on 2026-02-02

30

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

Sponsors

J

Johns Hopkins University

Lead Sponsor

M

Maryland Cigarette Restitution Fund

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating a pilot randomized controlled trial to study a computerized avatar-delivered intervention for tobacco cessation combined with support from community health workers (CHWs) and navigation to lung cancer screening. The study aims to assess recruitment feasibility, participant engagement, completion, and short-term smoking cessation outcomes in a residency clinic setting. Participants will be adults aged 50 and older who currently use tobacco and are considering quitting. The intervention group receives two sessions of computer-delivered counseling via a virtual counselor on a tablet, focusing on tobacco cessation and pharmacotherapy use, including nicotine replacement therapy (patches, gum, or lozenges). CHWs provide training on nicotine therapy use, frequent follow-up calls or video meetings for support, decision-making guidance on lung cancer screening, and assistance with healthcare navigation. The control group waits for six months without intervention and then receives the full computerized intervention and abbreviated CHW support. Participants will be assessed at baseline, 1 month, 3 months, and 6 months with questionnaires on demographics, tobacco use, and readiness to quit. The study measures acceptability and feasibility through module completion and CHW session attendance, as well as uptake of lung cancer screening and nicotine replacement therapy. Follow-up interviews with some participants will gather feedback on the intervention's acceptability. The total follow-up period is six months, with community support continuing during this time.

CONDITIONS

Brief Title

C-Raven, a Virtual Tobacco Cessation Intervention in Residency Clinics

Who Can Participate

Age: 50Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 50 or older
  • Current tobacco user with more than 100 cigarettes smoked in lifetime
  • Considering smoking cessation
  • Planning to remain in local area for at least 6 months
  • English speaking
Not Eligible

You will not qualify if you...

  • Contraindication to nicotine replacement therapy
  • Currently engaged in a formal smoking cessation program
  • Major cognitive or psychiatric impairment
  • Severe hearing impairment
  • Investigator discretion

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Baseline Assessment and Enrollment

Duration - 1 day

Participants complete informed consent, baseline questionnaires, and initial tobacco use assessments, followed by randomization to intervention or control groups.

1 visit (in-person)

Treatment

Duration - Up to 12 weeks

Participants in the intervention group receive two computer-delivered tobacco cessation counseling sessions with community health worker support and nicotine replacement therapy over 12 weeks. Control group participants do not receive intervention during this time.

2 in-person sessions plus remote follow-up up to twice weekly for 12 weeks

Follow-up

Duration - 6 months

Participants are assessed at 1 month, 3 months, and 6 months after baseline to evaluate smoking cessation progress, intervention acceptability, and uptake of lung cancer screening.

3 follow-up assessments

Trial Site Locations

Total: 1 location

1

Johns Hopkins University School of Medicine

Baltimore, Maryland, United States, 21205

Actively Recruiting

Loading map...

Research Team

A

Alejandra Ellison-Barnes, MD

H

Heidi Hutton, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Similar Trials

Quit4Life+: Adapting and Evaluating a Phone-Based Tobacco Us...

Nicotine Dependence

Actively Recruiting

2 locations

Evaluating the Efficacy of Cannabidiol for Reducing Cigarett...

Tobacco Use Disorder

Actively Recruiting

1 location

Early Withdrawal Exposure and Negative Affect Withdrawal (NA...

Tobacco Dependence

Actively Recruiting

1 location

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here