Actively Recruiting
C-SMART vs BE Well for Patients With Brain Tumors
Led by Virginia Commonwealth University · Updated on 2026-04-17
42
Participants Needed
1
Research Sites
99 weeks
Total Duration
On this page
Sponsors
V
Virginia Commonwealth University
Lead Sponsor
A
American Psychological Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn about the acceptability and feasibility of Cognitive Strategies, Mindfulness, and Rehabilitation Therapy (C-SMART) and Brain health Education and Wellness (BE Well) in adults with brain tumors and their caregivers. Participants will be assigned to one of the two groups: * Cognitive Strategies, Mindfulness, and Rehabilitation Therapy (C-SMART) is a recently developed virtual intervention combining both cognitive rehabilitation with mindfulness meditation training. The manualized program consists of 8 weekly 1:1 tele intervention sessions, targeting cognitive weaknesses identified from baseline cognitive testing. * Brain health Education and Wellness (BE Well) intervention consists of 8 weekly videos focused on maximizing brain health in the context of brain tumor. Participants will also be asked to: * participate in two in-person visits involving an MRI and neurocognitive tests * complete a survey the the beginning and end of the study * if in BE Well group, answer a few questions after watching each video
CONDITIONS
Official Title
C-SMART vs BE Well for Patients With Brain Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient of Virginia Commonwealth University Neuro-Oncology clinic
- Confirmed primary brain tumor diagnosis by histology or neuro-oncologist review of imaging
- At least one domain of neurocognitive function more than 1.5 standard deviations below average or estimated premorbid functioning
- More than 1 month post brain surgery and/or radiation therapy, if applicable
- Estimated premorbid intelligence greater than 75
- Age 18 years or older
- Primarily English speaking
- Caregivers must enroll with a patient meeting the above criteria
- Caregivers must be age 18 years or older
- Caregivers must be primarily English speaking
You will not qualify if you...
- Major neurocognitive impairment preventing participation, severe aphasia, or inability to understand and provide informed consent
- Inability to attend weekly telehealth appointments
- Clinically significant insomnia symptoms that interfere more than cognitive symptoms
- Less than 1 month post brain surgery and/or radiation therapy
- Unstable internet connection or inability to use teleconferencing software (an iPad will be provided if needed)
- Presence of metal in the body preventing safe MRI
- Pregnancy in females of childbearing years due to MRI risks
AI-Screening
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Trial Site Locations
Total: 1 location
1
Virginia Commonwealth University
Richmond, Virginia, United States, 23298
Actively Recruiting
Research Team
S
Sarah Braun, Ph.D
CONTACT
B
Brighton Payne, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
4
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