Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID07035171

CABGpreHAB- Home-based Multimodal Prehabilitation for Elective Patients Awaiting Coronary Artery Bypass Graft Surgery - a Feasibility Study Protocol

Led by Rigshospitalet, Denmark · Updated on 2025-06-29

50

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Patients with ischemic heart disease who are scheduled for elective coronary artery bypass graft (CABG) surgery often face challenges such as advanced age, frailty, other health conditions, and physical inactivity. These factors, along with the physical and psychological stress of surgery, can affect recovery after the operation. Traditionally, efforts to improve surgical outcomes focus on care during and after surgery, but the waiting period before surgery may offer a valuable opportunity for prehabilitation to boost patients' ability to recover. The study evaluates the feasibility of a home-based multimodal prehabilitation program for patients awaiting elective CABG surgery. This program combines web-based supervised exercise sessions, nutritional guidance, psychological support, and advice on smoking and alcohol cessation. Patients in the intervention group receive these additional preoperative supports alongside usual care, while the control group receives usual care alone. The intervention includes three exercise sessions per week via a tablet and weekly phone consultations with a specialized nurse. Participants will be involved from enrollment until 30 days after surgery. Researchers will monitor recruitment, retention, adherence to the prehabilitation program, and safety throughout the preoperative period. Various assessments will occur at baseline, the day before surgery, and 30 days post-surgery, including exercise capacity, muscle strength, nutritional status, quality of life, anxiety, depression, and lifestyle factors such as tobacco and alcohol use. The study aims to inform a larger future trial and improve patient outcomes using the pre-surgery period.

CONDITIONS

Brief Title

CABGpreHAB - a Feasibility Study Protocol

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Planned to have elective isolated first-time coronary artery bypass graft surgery
  • 18 years or older
  • At least two weeks before surgery
  • Speaks and understands Danish
  • Provides written informed consent
Not Eligible

You will not qualify if you...

  • Unstable angina pectoris or heart attack within the last two weeks
  • Left main stem stenosis greater than 50%
  • Left ventricular ejection fraction below 35%
  • Significant ventricular arrhythmia
  • Orthopedic or neurological conditions preventing exercise training
  • Physical limitations preventing participation in prehabilitation
  • Cognitive deficits disqualifying prehabilitation
  • Severe heart failure, NYHA Class IV
  • Lack of capacity to consent

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Prehabilitation

Duration - At least 2 weeks until the day before surgery

Participants randomized to the intervention group will receive a home-based multimodal prehabilitation program including exercise training via a web-based application, nutritional optimization, psychological support, and counseling on smoking and alcohol cessation. The control group will receive usual care.

Weekly phone calls and tele-exercise sessions three times per week

Surgery and Immediate Post-operative Care

Duration - Until hospital discharge

Participants undergo elective coronary artery bypass graft surgery and receive immediate post-operative care.

1 hospital stay starting on or days before surgery

Follow-up

Duration - 30 days post surgery

Participants are monitored for recovery and outcomes up to 30 days after surgery, including assessments of exercise capacity, muscle strength, physical activity, quality of life, and psychological status.

1 follow-up visit at approximately 30 days post surgery

Trial Site Locations

Total: 1 location

1

The Department of Heart and Lung Surgery, Copenhagen University hospital Rigshospitalet

Copenhagen, Denmark, 2100

Actively Recruiting

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Research Team

D

Dorte Baek Olsen, PhD student

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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