Actively Recruiting
Caffeine Consumption in Glaucoma Patients and Healthy Subjects
Led by Wills Eye · Updated on 2025-11-14
80
Participants Needed
1
Research Sites
417 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Caffeine is the most widely consumed drinking nutrient in the world. Caffeine effects various organs and the vascular system. It decreases ocular blood flow due to vasoconstriction.
CONDITIONS
Official Title
Caffeine Consumption in Glaucoma Patients and Healthy Subjects
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 90 years
- Diagnosis of primary open angle glaucoma (mild, moderate, or advanced)
- Healthy subjects with no eye disease
You will not qualify if you...
- Diseases affecting OCTA results, ophthalmic or systemic
- Greater than moderate cataract
- Nystagmus
- Inability to look at target
- Macular degeneration other than mild drusen or pigmentary changes
- Diabetic retinopathy
- Neovascular glaucoma or non-glaucoma optic neuropathies
- Current macular edema, prior laser to retina, inflammatory retinopathy or choroidopathy
- Keratoconus, corneal ectasia, central corneal scarring
- Rheumatologic diseases or Raynaud's phenomena
- Pregnant and lactating women
- Mental illness or alcohol addiction
- Pre-existing bladder symptoms, cardiac disease or sleep disorder
- Refractive spherical diopter greater than 5 or cylinder greater than 3
- Possible tolerance to caffeine (drinking more than 1 cup coffee per day)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Wills Eye Glaucoma Service
Philadelphia, Pennsylvania, United States, 19107
Actively Recruiting
Research Team
M
M. Reza Razeghinejad, MD
CONTACT
J
Jeanne Molineaux, COA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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