Actively Recruiting
Caloric Restriction In Sarcoma Patients Treated With Pre-Operative RT
Led by Massachusetts General Hospital · Updated on 2025-10-06
32
Participants Needed
1
Research Sites
569 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is being conducted to decrease the rate of surgical wound complications. The investigators are studying the effects that caloric restriction has on decreasing the rate of surgical wound complications.
CONDITIONS
Official Title
Caloric Restriction In Sarcoma Patients Treated With Pre-Operative RT
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age greater than 18 years
- Biopsy-proven soft tissue sarcoma located in the lower extremities
- Planned treatment with radiation therapy for primary or recurrent lower extremity soft tissue sarcoma followed by surgical resection
- Karnofsky Score of 60% or higher
- Body Mass Index of 20 kg/m2 or higher
- Protein levels within normal limits within 45 days before enrollment
- Normal kidney and liver function within 45 days before enrollment
- Normal blood counts within 45 days before enrollment
- Normal chemistries within 45 days before enrollment
You will not qualify if you...
- Current pregnancy or breastfeeding
- Diagnosis of other cancers within the last 5 years (in situ or invasive)
- Diabetes mellitus
- Current treatment with metformin
- Any condition preventing surgery, such as intractable nausea, allergic reaction to supplements, decision not to have surgery, or other medical conditions
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Massachusetts general Hospital
Boston, Massachusetts, United States, 02114
Actively Recruiting
Research Team
S
Santiago A Lozano-Calderón, MD, PhD
CONTACT
S
Shreya Halur, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here