Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07046767

CAMP RWE Trial: Amnion Grafts for Healing Hard-to-Heal Ulcers in RW Populations

Led by Capsicure, LLC · Updated on 2025-10-22

165

Participants Needed

7

Research Sites

41 weeks

Total Duration

On this page

Sponsors

C

Capsicure, LLC

Lead Sponsor

B

BioLab Holdings

Collaborating Sponsor

AI-Summary

What this Trial Is About

CAMP RWE Trial: A Multicenter hybrid platform trial comparing the effects of a prospective cohort treated with a tri-layer amnion graft or a single layer amnion graft to a coarsened exact matched retrospective control cohort of patients with hard-to-heal DFUs and VLUs

CONDITIONS

Official Title

CAMP RWE Trial: Amnion Grafts for Healing Hard-to-Heal Ulcers in RW Populations

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female 18 years of age and older
  • Non-healing venous leg ulcer or diabetic foot ulcer of more than 4 weeks duration with less than 50% reduction in wound size in the last 4 weeks
  • Wound size between 2 cm² and 25 cm²
  • If multiple eligible wounds, the largest wound will be selected as the index wound
  • Able and willing to follow protocol requirements
  • Signed informed consent
Not Eligible

You will not qualify if you...

  • Inability to follow the study protocol or visit schedule
  • Pregnancy
  • Child-bearing potential without appropriate contraception
  • Lactation
  • Treatment of the wound with engineered tissue or scaffold materials within 30 days before first treatment
  • Visible signs of wound improvement (50% reduction in surface area) within 4 weeks before enrollment
  • Other conditions that may compromise safety as judged by the investigator
  • Known contraindications to amniotic tissue grafts
  • Signs of wound infection requiring antibiotic treatment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 7 locations

1

FOMAT Medical Research

Oxnard, California, United States, 93030

Actively Recruiting

2

Solutions Medical Research

Coral Gables, Florida, United States, 33134

Actively Recruiting

3

Nova Medical Services - Research Division LLC

Miami, Florida, United States, 33176

Actively Recruiting

4

Indiana University Health Methodist Hospital

Indianapolis, Indiana, United States, 46202

Actively Recruiting

5

St. Louis Foot and Ankle, LLC

St Louis, Missouri, United States, 63128

Actively Recruiting

6

Jevlos Health, Inc

Syosset, New York, United States, 11791

Actively Recruiting

7

Hope Vascular and Podiatry

Houston, Texas, United States, 77054

Actively Recruiting

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Research Team

M

Marissa Docter, RN, BSN, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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