Actively Recruiting
Campylobacter Spp. Bone and Joint Infection: a Retrospective Cohort Study
Led by Hospices Civils de Lyon · Updated on 2024-05-22
200
Participants Needed
1
Research Sites
25 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Campylobacter bacteria, a Gram-negative bacillus commensal in the digestive tract of many animals and mainly responsible for human infections with digestive origins, has been little studied in the field of osteoarticular infections (OAI). Campylobacter spp. are, however, well described, mainly for C. fetus, and pose a dual therapeutic problem: i) a capacity for persistence due to the capacity of most strains to form biofilm; and ii) potential resistance to many antibiotics. The management of IOA caused by Campylobacter spp. is not codified, and is based on small series of cases reported in the literature.
CONDITIONS
Official Title
Campylobacter Spp. Bone and Joint Infection: a Retrospective Cohort Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults older than 18 years
- Diagnosed with osteoarticular infection involving Campylobacter spp. between 01/01/2013 and 12/31/2022
- Diagnosis includes septic arthritis confirmed by clinical signs and positive joint fluid culture or PCR for Campylobacter
- Diagnosis includes spondylodiscitis confirmed by clinical signs, MRI, and positive blood cultures or biopsy for Campylobacter
- Diagnosis includes osteitis or osteomyelitis confirmed by clinical and radiological signs and positive bone biopsy or intraoperative sample for Campylobacter
- Infection on joint prosthesis or osteosynthesis equipment with documented Campylobacter infection meeting criteria for probable or confirmed infection
- Patient informed and did not object to study participation
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
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Trial Site Locations
Total: 1 location
1
Service des maladies infectieuses et tropicales - Hôpital de la Croix-Rousse
Lyon, France, 69317
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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