Actively Recruiting

Phase 3
Age: 18Years +
All Genders
NCT02000089

The Cancer of the Pancreas Screening-5 CAPS5)Study

Led by Johns Hopkins University · Updated on 2025-10-09

9000

Participants Needed

9

Research Sites

803 weeks

Total Duration

On this page

Sponsors

J

Johns Hopkins University

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Johns Hopkins clinical research office quality assurance group will monitor and audit this study at Johns Hopkins. The Sub Investigator at each site will be responsible for internal monitoring at their site.

CONDITIONS

Official Title

The Cancer of the Pancreas Screening-5 CAPS5)Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Hereditary Pancreatitis or Peutz-Jeghers Syndrome
  • Strong family history of pancreas cancer on one side of the family
  • Confirmed germline mutation carrier (including BRCA2, FAMMM (CDKN2A/p16), PALB2, BRCA1, ATM, HNPCC, Lynch Syndrome genes, PRSS1, PRSS2, SPINK1, CFTR)
  • Scheduled for endoscopic evaluation of pancreas
Not Eligible

You will not qualify if you...

  • Medical conditions or blood clotting problems that prevent endoscopy
  • Prior surgeries that prevent optimal endoscopic ultrasound, such as partial or complete gastrectomy with Bilroth or Roux-en-Y anastomosis
  • Narrowing or blockage in the upper digestive tract that blocks echoendoscope passage
  • Poor overall health status
  • Unable to provide informed consent
  • Pregnancy

AI-Screening

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Trial Site Locations

Total: 9 locations

1

Yale University

New Haven, Connecticut, United States, 06520

Actively Recruiting

2

Johns Hopkins Hospital

Baltimore, Maryland, United States, 21287

Actively Recruiting

3

Dana Farber Cancer Center, Harvard University

Boston, Massachusetts, United States, 02215

Actively Recruiting

4

University of Michigan

Ann Arbor, Michigan, United States, 48109

Actively Recruiting

5

NYU Langone Medical Center

New York, New York, United States, 10016

Actively Recruiting

6

Columbia University Medical Center

New York, New York, United States, 10032

Actively Recruiting

7

Case Comprehensive Cancer Center, Case Western Medical Reserve

Cleveland, Ohio, United States, 44106

Actively Recruiting

8

University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

9

University of Pittsburgh

Pittsburgh, Pennsylvania, United States, 15213

Actively Recruiting

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Research Team

H

Hilary Cosby, RN

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

9

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