Actively Recruiting

Age: 18Years +
All Genders
NCT06567704

Cancer-related Fatigue During Maintenance Immunotherapy for Non-small Cell Lung Cancer (NSCLC): a Qualitative Study

Led by Wake Forest University Health Sciences · Updated on 2026-02-03

20

Participants Needed

2

Research Sites

92 weeks

Total Duration

On this page

Sponsors

W

Wake Forest University Health Sciences

Lead Sponsor

A

Atrium Health Levine Cancer Institute

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this research is to understand cancer related fatigue in patients with non-small cell lung cancer (NSCLC), who are being treated with an immune checkpoint inhibitor.

CONDITIONS

Official Title

Cancer-related Fatigue During Maintenance Immunotherapy for Non-small Cell Lung Cancer (NSCLC): a Qualitative Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years of age or older at the time of consent
  • Able to speak, read, and understand English
  • Diagnosed with non-small cell lung cancer (NSCLC) with one of the following: advanced/metastatic disease currently receiving immunotherapy alone; locally advanced disease currently receiving immunotherapy alone after thoracic radiation; or post-resection receiving immunotherapy alone after completing all other perioperative treatment
  • Planned to continue immunotherapy for at least three months after enrollment
  • Completed at least two cycles of immunotherapy
  • Self-reported cancer-related fatigue impacting daily function
Not Eligible

You will not qualify if you...

  • Received chemotherapy (including maintenance pemetrexed) within the past 3 months
  • Received radiation therapy within the past 3 months, except for a short course of palliative radiation therapy (up to 20 Gy in up to 5 fractions)
  • Diagnosis of dementia
  • Anemia with hemoglobin less than 10 g/dL
  • Sarcopenia currently treated with prescribed appetite stimulants (e.g., megestrol)
  • Untreated hypothyroidism
  • Symptomatic heart failure
  • Oxygen-dependent lung disease
  • Unable to complete interviews due to cognitive impairment per investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Atrium Health Levine Cancer

Charlotte, North Carolina, United States, 28204

Actively Recruiting

2

Wake Forest Baptist Comprehensive Cancer Center

Winston-Salem, North Carolina, United States, 27157

Actively Recruiting

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Research Team

M

Megan Lattanze

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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