Actively Recruiting

Phase 1
Age: 21Years - 55Years
All Genders
Healthy Volunteers
NCT04385082

Cannabis Effects as a Function of Sex

Led by University of California, Los Angeles · Updated on 2026-03-20

160

Participants Needed

1

Research Sites

312 weeks

Total Duration

On this page

Sponsors

U

University of California, Los Angeles

Lead Sponsor

N

National Institute on Drug Abuse (NIDA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this research is to assess the impact of cannabis on the analgesic and abuse-related effects between men and women

CONDITIONS

Official Title

Cannabis Effects as a Function of Sex

Who Can Participate

Age: 21Years - 55Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or non-pregnant female aged 21-55 years
  • Use cannabis an average of 1-7 days per week
  • Not currently seeking treatment for cannabis use
  • Urine test positive for recent cannabis use for heavy users
  • No reported adverse effects with cannabis smoking in light users
  • Body Mass Index between 18.5 and 34 kg/m2
  • Able to perform all study procedures
  • Females must use a non-hormonal effective form of birth control
  • Females must be regularly cycling
Not Eligible

You will not qualify if you...

  • Meet DSM-V criteria for any substance use disorder other than nicotine, caffeine, or cannabis use disorder
  • Use other illicit drugs in the prior 4 weeks
  • History or current severe psychiatric illness or medical condition risking adverse events or interfering with study participation
  • Current use of medical cannabis, prescription analgesics, or medications affecting study outcomes
  • Current pain
  • Insensitivity to the cold water stimulus of the Cold Pressor Test
  • Females using hormonal contraceptives

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of California, Los Angeles

Los Angeles, California, United States, 90095

Actively Recruiting

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Research Team

Z

Ziva Cooper, PhD

CONTACT

V

Vincent Acebo

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

BASIC_SCIENCE

Number of Arms

3

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Cannabis Effects as a Function of Sex | DecenTrialz