Actively Recruiting
Cannabis, Linked Emotions, and Adolescent Risk Study
Led by Massachusetts General Hospital · Updated on 2026-03-03
200
Participants Needed
1
Research Sites
218 weeks
Total Duration
On this page
Sponsors
M
Massachusetts General Hospital
Lead Sponsor
N
National Institute on Drug Abuse (NIDA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this study is to disentangle relationships between acute cannabis use and withdrawal on proximal depression and suicide risk and recovery in adolescents ages 12-18 years by incorporating time-varying patterns of substance use, mood, and SI. This project aims to guide the development of scalable, individualized, accessible, and affordable interventions aimed to reduce depression and suicide risk among adolescents.
CONDITIONS
Official Title
Cannabis, Linked Emotions, and Adolescent Risk Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ages 12 to 18 years
- Current daily or near daily cannabis use (4 or more days per week on average)
- Score of 5 or higher on PHQ-9 depression questionnaire
- Access to an internet-capable smartphone (iOS or Android)
- Provide at least one collateral contact for safety monitoring
- Provide informed assent or consent (parent/guardian consent if under 18 years old)
- Respond to more than 50% of EMA prompts during the first phase
- No immediate plan to stop cannabis use in the next 3 months
- Positive cannabis result on baseline urine test
You will not qualify if you...
- Any condition that impairs ability to understand or participate, including being intoxicated at consent
- Cannabis use more than 4 times per day on average
- Inability to speak or write English fluently
- Severe cognitive impairment such as due to psychosis, intellectual disability, developmental delay, or neurodegenerative disease
- Current diagnosis of epilepsy
- Being under legal protection of the government or state (wards of the state)
- Incorrect response to EMA suicidality response time knowledge check
- Inability to wear the Fitbit device used in the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Massachusetts General Hopsital
Boston, Massachusetts, United States, 02114
Actively Recruiting
Research Team
R
Randi M Schuster, PhD
CONTACT
J
Julia Jashinski, MSW
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
3
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