Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07268365

Is Cap Assisted Endoscopy Useful in Acute Upper Gastrointestinal Bleeding ?

Led by Centre Hospitalier Universitaire, Amiens · Updated on 2025-12-05

72

Participants Needed

1

Research Sites

54 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

High digestive bleeding (HDH) is a medical emergency associated with high morbidity and mortality rates and significant healthcare costs. Upper endoscopy can locate the bleeding and treat it. However, the source of bleeding can be difficult to identify, even for the most experienced endoscopists, due to the location of the bleeding (posterior wall of the bulb, gastric or duodenal folds, papillary region, esophagogastric junction), instability of the tube due to gastric and pyloric contractions and respiratory movements, leading to longer procedure times, hemostasis failure, or even the absence of bleeding visualization. The use of a cap attached to the endoscope facilitates exploration of blind areas of the colonic mucosa located behind folds, thus reducing the rate of missed polyps and cecal intubation time. To date, there is no study evaluating the systematic use of a cap in patients with suspected high digestive bleeding. A series of four cases demonstrated its benefit, allowing for better exposure of the bleeding lesion, better unfolding of intestinal folds, and thus a more effective and quicker hemostatic treatment.

CONDITIONS

Official Title

Is Cap Assisted Endoscopy Useful in Acute Upper Gastrointestinal Bleeding ?

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient older than 18 years
  • Suspected upper gastrointestinal bleeding with melena or hematemesis
  • Glasgow Blatchford score greater than 8
  • Undergoing upper gastroscopy at Amiens University Hospital
  • Willing to have follow-up at Amiens University Hospital
  • Presence of gastric or duodenal ulcer requiring endoscopic hemostasis (FORREST Ia, Ib, IIa, IIb)
  • No opposition to participating in the study
  • No guardianship or curatorship
Not Eligible

You will not qualify if you...

  • Clinical suspicion of portal hypertension
  • Known liver failure
  • Digestive bleeding from lesions beyond the second part of the duodenum
  • Digestive bleeding from variceal lesions (esophageal or gastric varices)
  • Bleeding associated with esophagitis
  • Bleeding associated with angiodysplasias

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Centre Hospitalier Universitaire d'Amiens

Amiens, Picardie, France, 80000

Actively Recruiting

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Research Team

C

Clara YZET, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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