Actively Recruiting

Phase Not Applicable
Age: 0Months - 50Years
FEMALE
Healthy Volunteers
ID06984081

CAPA In-vitro Oocyte Maturation for Female Infertility

Led by Chinese University of Hong Kong · Updated on 2025-12-08

100

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying in vitro oocyte maturation (IVM), a gentler assisted reproductive technology, in women facing infertility. This approach may be especially helpful for patients with polycystic ovary syndrome (PCOS) or those seeking fertility preservation due to treatments like chemotherapy. The study aims to explore the benefits of IVM, including its lower health risks and reduced costs compared to traditional ovarian stimulation methods. The study evaluates CAPA-IVM, a procedure where eggs mature outside the body, unlike classical IVF where ovarian stimulation affects the patient directly. This method avoids the typical risks and burdens associated with systemic ovarian stimulation. Participants will undergo the CAPA-IVM procedure, focusing on egg maturation outside the body without hormonal treatments. Participants will be monitored for the number of mature eggs obtained one week after the procedure. The study involves women and girls up to 50 years old who are seeking fertility preservation or oocyte retrieval services. Researchers will assess outcomes related to egg maturity while ensuring safety and minimizing patient burden throughout the process. The total study duration extends until May 2032.

CONDITIONS

Brief Title

CAPA In-vitro Oocyte Maturation

Who Can Participate

Age: 0Months - 50Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged from 0 to 50 years old
  • Patients seeking fertility preservation services
  • Patients seeking oocyte retrieval services
Not Eligible

You will not qualify if you...

  • Patients unable to provide consent or assent due to significant psychiatric problems or cognitive delay

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 1 week

Participants undergo CAPA In-vitro Oocyte Maturation, where oocytes are treated and matured outside the woman's body without systemic ovarian stimulation.

1 treatment visit

Trial Site Locations

Total: 1 location

1

Prince of Wales Hospital

Hong Kong, Hong Kong

Actively Recruiting

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Research Team

P

Pui Wah Jacqueline Chung

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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