Adapting the CAPABLE Program to Support Active Status and Improve Health for Adults Awaiting Kidney Transplant

What this Trial Is About

This research aims to adapt the CAPABLE program as CAPABLE Transplant to help adults awaiting kidney transplant who face barriers to being classified as active on the transplant waitlist and to support prehabilitation for pre-frail or frail patients. It includes an open-label pilot and a randomized waitlist control trial to test feasibility and acceptability among low-income active kidney transplant waitlist candidates. The study focuses on improving waitlist status and pre-surgical health in this vulnerable population. Participants receive a tailored set of interventions over 4 months delivered by an occupational therapist, a registered nurse, and a handy worker through home visits. The program includes about 6 occupational therapy visits and 4 nursing visits, each lasting up to one hour. The open-label pilot with 3 individuals will help refine the program before testing it in a randomized trial where 20 participants receive the intervention immediately, and 20 others serve as waitlist controls before receiving it. During the study, participants are assessed at baseline, after the 4-month intervention, and again after the waitlist control period. Researchers will evaluate waitlist status using data from the National Kidney Registry and measure changes in self-efficacy, pain, depression, social engagement, fatigue, frailty, health team communication, and functional abilities using validated questionnaires and scales. The study runs from 2025 to 2027, aiming to support improved quality of life and transplant readiness.

CAPABLE Transplant