Actively Recruiting
CAPACITY (Cardiac Amyloidosis and Physical ACtivITY) Study
Led by Wake Forest University Health Sciences · Updated on 2025-07-28
50
Participants Needed
1
Research Sites
175 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Exercise training in patients with heart failure and preserved ejection fraction (HFpEF) has been associated with an improvement in cardiorespiratory fitness and quality of life.
CONDITIONS
Official Title
CAPACITY (Cardiac Amyloidosis and Physical ACtivITY) Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age > 18
- New York Heart Association (NYHA) Class I-III Heart Failure
- Able to Exercise
- On stable treatment for their cardiac amyloidosis or under active surveillance
- Life expectancy of at least 6 months
- Ability to understand and the willingness to sign a written informed consent document in English, and the willingness/ability to comply with the protocol activities
- Participant must be able and willing to follow the cardiac rehabilitation activities
You will not qualify if you...
- Inability to provide informed consent
- Inability to commit to in-person supervised exercise sessions for three one-hour sessions a week for 12 weeks
- NYHA Class IV Heart Failure
- Pulmonary disease requiring home oxygen
- Gait instability or history of prior falls
- In the opinion of the Principal Investigator, have a clinically significant comorbid disease that is likely to affect the ability of the patient to complete the trial, interfere with their ability with measurement of self-reported outcomes.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Sanger Heart and Vascular Institute
Charlotte, North Carolina, United States, 28204
Actively Recruiting
Research Team
D
Dana B Amaro, RN
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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