Studying Intestinal Microbiota Sampling Using Capsules in Adults with IBS and Functional Gastrointestinal Disorders

What this Trial Is About

Researchers are evaluating the intestinal microbiota in healthy individuals and those with Irritable Bowel Syndrome IBS or functional gastrointestinal diseases such as bloating, diarrhea, and constipation. The study aims to collect and analyze samples from the intestinal microbiome to better understand these conditions. Participants include adults aged 18 to 70 years who meet specific health criteria and symptom profiles. The study involves sampling saliva, feces, and intestinal microbiota using a microbiome sampling capsule. This capsule is designed to collect intestinal fluid, and the goal is to successfully collect 50 microliters of fluid from over 90% of capsules used. Participants include both healthy individuals and those diagnosed with IBS or functional gastrointestinal disorders. The study does not involve drug treatments but focuses on observational sampling and analysis. Participants will provide samples of saliva, feces, and intestinal fluid collected by the capsule. The study includes monitoring for the presence of live bacteria in these samples. Participants must comply with study requirements including pregnancy testing and contraceptive use if applicable. Researchers will evaluate the quality and quantity of samples collected over a study period lasting from one to four years. Safety and adherence are monitored throughout the study with no intervention-based treatments administered.

Capsule Microbiota Sampling in IBS/Functional Gastrointestinal Disease