Actively Recruiting
Capturing Key MG-symptoms Using Smartphone Recordings.
Led by Leiden University Medical Center · Updated on 2025-09-09
225
Participants Needed
2
Research Sites
54 weeks
Total Duration
On this page
Sponsors
L
Leiden University Medical Center
Lead Sponsor
H
Huma
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study will make use of a cross-sectional design of MG patients and non-MG participants to quantitatively assess key MG symptoms, and to explore the applicability of machine learning algorithms to their measurement.
CONDITIONS
Official Title
Capturing Key MG-symptoms Using Smartphone Recordings.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 6 18 years
- Ability to understand the study and provide written informed consent
- For MG patients: diagnosed with myasthenia gravis (ocular or generalized) per Dutch guidelines
- For MG patients: MGFA Clinical Classification I-IV severity
- For MG patients: have at least one symptom of interest (dysarthria, dysphonia, proximal arm fatigue, or ptosis)
- For non-MG participants: no diagnosis or suspicion of MG
- For non-MG participants: no history of symptoms of interest (dysarthria, dysphonia, proximal arm fatigue, or ptosis)
You will not qualify if you...
- Unwilling to be audio-recorded
- Unwilling to be video-recorded
- Currently participating in a clinical trial of an investigational drug
- Used immediate release pyridostigmine within 12 hours before participation or on prolonged release pyridostigmine
- Cognitive or physical limitations affecting ability to complete study procedures
- For MG patients: upper-limb amputation or non-verbal status
- For MG patients: diagnosed neurological disease causing muscle weakness other than MG
- For non-MG participants: limited upper limb mobility or speech impairment of any cause
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Leiden University Medical Center
Leiden, South Holland, Netherlands, 2333 ZA
Not Yet Recruiting
2
Leiden University Medical Center
Leiden, Netherlands
Actively Recruiting
Research Team
M
Martijn R Tannemaat, MD, PhD
CONTACT
Y
Yvonne JM Campman, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here