Actively Recruiting
CAR-T Immunomonitoring in Multiple Myeloma (CART I5M)
Led by Poitiers University Hospital · Updated on 2026-02-18
60
Participants Needed
1
Research Sites
346 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Multiple myeloma patients can be treated with cell therapy, which uses some of their own modified white blood cells (T lymphocytes) to target a protein (BCMA, or B-cell maturation antigen) found on the surface of the myeloma plasma cells. These modified T lymphocytes are called CAR T cells (chimeric antigen receptor T cells). The long-term persistence of these modified lymphocytes, or CAR-BCMA, is a recognized indicator of a good response to treatment. This research aims to study certain markers related to CAR-BCMA cell persistence. This research will be carried out in collaboration with the Laboratory of Ischemia Reperfusion, Metabolism and Sterile Inflammation in Transplantation (IRMETIST) INSERM unit U1313, located at the University of Poitiers. The proposed project will contribute to better patient care in the field of oncology, by identifying immunological cellular markers predictive of an effective response to anti-cancer treatments and/or immunotherapeutic targeting.
CONDITIONS
Official Title
CAR-T Immunomonitoring in Multiple Myeloma (CART I5M)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient aged 18 and over
- Patient with Multiple Myeloma according to international recommendations
- Patient about to receive CAR-T cell therapy in accordance with the rules and authorizations in France
You will not qualify if you...
- Severely impaired physical and/or psychological health that may affect compliance with the study
- Simultaneous participation in another study with an ongoing exclusion period
- Individuals receiving enhanced protection such as minors, pregnant or breastfeeding women, individuals deprived of liberty, residents in healthcare or social care facilities, adults under legal guardianship, and patients in emergency situations
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Chu de Poitiers
Poitiers, France, 86000
Actively Recruiting
Research Team
A
ARTHUR BOBIN
CONTACT
S
STEPHANIE NOEL
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
1
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