Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06209684

Carbofix Pedicle Screw System: Evaluation of the Clinical and Radiographic Outcomes of the Use of a Carbon Fiber Device Compared to Titanium Devices in Patients Undergoing Spinal Arthrodesis for Degenerative Spinal Diseases

Led by Istituto Ortopedico Rizzoli · Updated on 2025-01-17

118

Participants Needed

1

Research Sites

260 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Previous clinical study carried out on cancer patients at IOR Spine Surgery (approved in October 2014). The carbon device is indicated in patients suffering from vertebral tumors who need stabilization and will then carry out radiotherapy, because carbon has a practically zero level of interference with ionizing radiation. Carbon also allows for better visualization of the implants on MRI/CT and X-ray. There are no studies in the literature analyzing the use of carbon fiber devices in lumbar degenerative pathologies. 118 patients suffering from degenerative spinal pathology requiring 1 or 2 levels of lumbar or lumbosacral fusion will be valutated.

CONDITIONS

Official Title

Carbofix Pedicle Screw System: Evaluation of the Clinical and Radiographic Outcomes of the Use of a Carbon Fiber Device Compared to Titanium Devices in Patients Undergoing Spinal Arthrodesis for Degenerative Spinal Diseases

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients suffering from degenerative spinal pathology or spondylolisthesis who require instrumented stabilization on 1-2 levels
  • Age greater than or equal to 18 years
  • Ability to understand and sign the informed consent to the study and to follow the required follow-ups
Not Eligible

You will not qualify if you...

  • Metabolic bone disease
  • History of Paget's disease or other osteodystrophies, including renal osteodystrophy, hyperthyroidism, hypothyroidism, Ehlers-Danlos syndrome, osteogenesis imperfecta, achondroplasia
  • Neoplastic disease
  • History of mental disorder or current psychiatric treatment
  • Pregnancy
  • Immunodeficiency diseases
  • Infectious bone disease (discitis, osteomyelitis)
  • Treatment with drugs that can interfere with bone metabolism
  • Inability to understand and sign the informed consent to the study and to follow the required follow-up visits
  • Alcohol and/or drug abuse
  • Obesity
  • Metal allergy
  • Participation in other studies on drugs or devices within 30 days

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Istituto Ortopedico Rizzoli

Bologna, Italy, 40136

Actively Recruiting

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Research Team

A

Alessandro Gasbarrini, MD

CONTACT

C

Cristiana Griffoni, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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