Actively Recruiting
Carbon Ion Radiotherapy for Locally Advanced Lung Cancer in Elderly Patients
Led by Jian Chen · Updated on 2025-06-13
29
Participants Needed
1
Research Sites
96 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To observe the effect and toxicity of carbon ion radiotherapy on local advanced non-small cell lung cancer over 75 years old patients. Systemic therapy could be targeted therapy, chemotherapy or immunotherapy.
CONDITIONS
Official Title
Carbon Ion Radiotherapy for Locally Advanced Lung Cancer in Elderly Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Older than 75 years old.
- ECOG general status score of 0-2.
- Primary non-small cell lung cancer confirmed by histology or cytology, stage IIb-IIIc (T1-4N1-3M0).
- Medically inoperable or patient refuses surgery.
- Adequate organ function including blood, lung, cardiac, liver, and kidney functions as specified.
- Signed informed consent.
You will not qualify if you...
- Squamous cell carcinoma patients treated with bevacizumab before carbon ion radiotherapy.
- Presence of uncontrolled other malignant tumors.
- Particle radiotherapy plans not meeting dose coverage or organ dose constraints.
- Prior chest radiation therapy or radioactive particle implantation.
- Presence of cardiac pacemakers or internal metal implants affecting radiation.
- HIV positive, active hepatitis virus replication needing therapy but unable to receive it, or active syphilis.
- History of mental illness hindering treatment completion.
- Serious comorbidities interfering with radiotherapy, including acute infections, recent heart events, severe respiratory conditions, impaired immune function, radiation-sensitive diseases, or others affecting particle therapy.
- Any other conditions deemed inappropriate by the physician for study participation.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shanghai Proton and Heavy Ion Center
Shanghai, Shanghai Municipality, China, 201513
Actively Recruiting
Research Team
J
Jing Li
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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