Actively Recruiting
Card14gene (rs34367357 ) Polymorphism in Egyptian Psoriatic and Psoriatic Arthritis Patient
Led by South Valley University · Updated on 2025-03-11
50
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Psoriasis is a chronic, immune-mediated, multisystemic, inflammatory disease caused by the interaction of multiple susceptibility genes and environmental factors that affects 1-3% of the population worldwide .Psoriasis also is a chronic inflammatory skin disease characterized by scaly indurated erythema. Psoriatic arthritis (PsA) is an autoimmune and chronic musculoskeletal disorder that is associated with psoriasis of the skin . Its presentation can vary from subtle manifestations to highly destructive forms. Joint pain, stiffness and swelling are the most common symptoms.
CONDITIONS
Official Title
Card14gene (rs34367357 ) Polymorphism in Egyptian Psoriatic and Psoriatic Arthritis Patient
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 years and above
- Clinically diagnosed with moderate to severe psoriasis
- Psoriasis Area and Severity Index (PASI) score from 5 to 10% of body surface area
- Involvement of greater than 10% of the body surface area
- With or without psoriatic arthritis
You will not qualify if you...
- Other autoimmune conditions such as rheumatoid arthritis or systemic lupus erythematosus
- Pregnancy or breastfeeding
- Currently receiving immunosuppressive or systemic therapies
- Known genetic disorders affecting immune system function
- Liver or kidney impairment
- Allergy or contraindication to methotrexate
- Active or uncontrolled infections, including chronic infections like tuberculosis
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Qina University hospital, South Valley University Hospital
Qina, Egypt
Actively Recruiting
Research Team
M
Marwa Naguib Ahmed, MSc
CONTACT
S
Soheir Abdel-Hamid Ali
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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