Actively Recruiting

All Genders
NCT06715579

Cardiac Angiosarcoma International Registry

Led by Immune Oncology Research Institute · Updated on 2026-02-18

500

Participants Needed

1

Research Sites

521 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Primary cardiac angiosarcomas (PCA) are highly aggressive malignant heart tumors arising from the endothelial cells (ECs) lining the blood vessels of the heart and account for approximately 25%-30% of all primary cardiac malignancies. It is considered to be the most fatal and aggressive primary cardiac malignancy. This international registry aims to establish a large multicenter database of patients with cardiac angiosarcoma. Our objectives are: 1. Collect clinical data, including demographics, medical history, treatments, and outcomes, to build a comprehensive database. 2. Analyze data to evaluate and identify genetic, environmental, or lifestyle risk factors for cardiac angiosarcoma. 3. Evaluate the effectiveness of various treatments (surgery, chemotherapy, immunotherapy, radiation) to inform best practices. 4. Develop evidence-based guidelines and recommendations for prevention, diagnosis, treatment, and management based on registry data.

CONDITIONS

Official Title

Cardiac Angiosarcoma International Registry

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Confirmed diagnosis of cardiac angiosarcoma by histopathological examination, including subtypes like hemangiosarcoma and epithelioid hemangiosarcoma
  • Diagnosis made between January 2015 and January 2035
  • Participants from various geographical locations
  • Patients who have received any treatment (surgery, chemotherapy, immunotherapy, or radiation) for cardiac angiosarcoma
  • Informed consent obtained for prospective patients
  • Availability of relevant clinical data including demographics, tumor details, treatments, and outcomes
  • Willingness to participate in follow-up assessments
Not Eligible

You will not qualify if you...

  • Patients who do not provide informed consent
  • Cases where heart involvement is due to spread from another primary cancer

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Yeolyan Hematology and Oncology Center

Yerevan, Armenia, 0014

Actively Recruiting

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Research Team

A

Aharon Tsaturyan, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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