Clinical Trial on Strategic AED Placement and Local Resident Activation to Improve Cardiac Arrest Survival in High-risk Residential Areas
Led by Emergency Medical Services, Capital Region, Denmark · Updated on 2023-09-15
260
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
This research aims to increase the rates of bystander defibrillation during out-of-hospital cardiac arrests in densely populated residential areas with many cardiac arrest incidents. Despite the growing number of Automated External Defibrillators AEDs, survival and defibrillation rates remain low in these areas. The study focuses on improving bystander defibrillation and 30-day survival through strategic AED placement and resident involvement as citizen responders.
The study compares two approaches standard emergency response with ambulance and physician-staffed mobile care units plus activation of citizen responders via the Heart Runner app, against an enhanced intervention. The enhanced intervention adds strategically placed AEDs within a 1.5-minute walking distance to residences, registration of AEDs with emergency dispatch, and training courses for about 120 residents per area in CPR and AED use to recruit them as citizen responders.
Participants will be part of emergency calls for suspected cardiac arrest, where dispatchers provide telephone-assisted CPR instructions and guide bystanders to retrieve AEDs if available. Data from AED use will be collected. The study measures bystander defibrillation rates up to five years after intervention and 30-day survival post-cardiac arrest. Participation involves monitoring cardiac arrest cases, AED deployment, citizen responder activation, and outcomes within the study areas.
CONDITIONS
Brief Title
Cardiac Arrest in Residential Areas With Mobile First-responder Activation
Research Team
A
Anne J Jørgensen, MD
F
Fredrik Folke, MD, PhD
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Emergency Medical Services, Capital Region, Denmark
Lead Sponsor
TrygFonden, Denmark
Collaborating Sponsor
Who Can Participate
Age: 8Years +
All Genders
Eligibility Criteria
You may qualify if you...
Witnessed cardiac arrest registered in the Danish Cardiac Arrest Registry within study sites
Cardiac arrest must be witnessed
Cardiac arrest with non-traumatic cause (excluding intoxication, drowning, or suicide)
You will not qualify if you...
Cardiac arrest occurring in a nursing home
Cardiac arrest not treated by emergency medical services for ethical reasons or obvious signs of death
Suspected cardiac arrest not verified as true cardiac arrest
Cardiac arrests witnessed by emergency medical personnel
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Implementation
Duration - Up to five years
Participants in intervention areas receive strategically deployed AEDs and some residents are trained in CPR and AED use to act as citizen responders activated through an app during cardiac arrests.
Long-term Monitoring
Duration - Up to five years
Participants are observed for bystander defibrillation and 30-day survival after cardiac arrest.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Published Research Related To This Trial
Community intervention to improve defibrillation before ambulance arrival in residential neighbourhoods with a high risk of out-of-hospital cardiac arrest: study protocol of a cluster-randomised trial (the CARAMBA trial).
Anne Juul Grabmayr, Carolina Malta Hansen, Nanna Bo...