Actively Recruiting
A Prospective Study to Assess Patient-Reported Cardiac Quality of Life in Adults With Hypertrophic Cardiomyopathy, Thoracic Aortic Dilatation, and Radiation-Induced Heart Disease
Led by The Cleveland Clinic · Updated on 2025-08-20
1200
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying the quality of life in adults with hypertrophic cardiomyopathy (HCM), thoracic aortic dilatation (TAD), and radiation-induced heart disease (RIHD) who are not suitable candidates for surgery. This observational study aims to understand how these heart conditions affect patients' daily lives and well-being. The research seeks to identify risk factors linked to lower quality of life and changes over time to improve long-term management. Participants are adults diagnosed with HCM, TAD, or RIHD who are visiting the Cleveland Clinic for the first time for cardiac evaluation without prior or planned surgery. They will complete the Cardiac Quality of Life (QOL) Survey electronically at three points: baseline, 3 months, and 9 months. The survey covers five areas—global, physical, emotional, social, and spiritual health—and measures self-efficacy and resilience. During the study, participants will provide information through these surveys to help assess their health status across multiple domains. Researchers will compare results at 3 and 9 months to baseline to understand changes in quality of life and the impact of heritability and radiation-induced disease. The total participation time is about nine months, with ongoing monitoring through outpatient clinic visits and electronic questionnaires.
CONDITIONS
Brief Title
A Cardiac Disease Quality of Life Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 to 70 years at the time of consent
- Confirmed diagnosis of hypertrophic cardiomyopathy, thoracic aortic dilatation, and/or radiation-induced heart disease
- Being seen for the first time at the Cleveland Clinic Main Campus for a comprehensive cardiac evaluation
- Access to a phone, computer, or tablet with internet to complete follow-up questionnaires
You will not qualify if you...
- Previous surgery or planned surgery within nine months for hypertrophic cardiomyopathy or thoracic aortic dilatation
- Inability or unwillingness to comply with study requirements as judged by the investigator
- Inability to provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 9 months
Participants complete the Cardiac Quality of Life Survey to assess their health status across multiple domains over time.
3 electronic survey completions (baseline, 3 months, and 9 months)
Trial Site Locations
Total: 1 location
1
Cleveland Clinic
Cleveland, Ohio, United States, 44195
Actively Recruiting
Research Team
M
Milind Desai, M. D.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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