What is this study trying to find out about heart disease?

This study aims to understand how hypertrophic cardiomyopathy, thoracic aortic dilatation, and radiation-induced heart disease affect patients' quality of life. Researchers are gathering information on physical, emotional, social, and spiritual health impacts. The goal is to better manage the long-term effects of these heart conditions.

Who may be eligible for this heart disease clinical trial?

Adults aged 18 to 70 with a confirmed diagnosis of hypertrophic cardiomyopathy, thoracic aortic dilatation, or radiation-induced heart disease may be eligible. Participants should be visiting the clinic for a cardiac evaluation and have access to a device and internet to complete surveys. Please review eligibility criteria for more details.

Is there any cost to participate in this heart disease clinical trial?

Study-related care, including the surveys and all study visits, is provided at no cost. However, personal travel expenses may vary and are not guaranteed to be covered.

Actively Recruiting

Age: 18Years - 70Years

All Genders

ID04080492

A Prospective Study to Assess Patient-Reported Cardiac Quality of Life in Adults With Hypertrophic Cardiomyopathy, Thoracic Aortic Dilatation, and Radiation-Induced Heart Disease

Led by The Cleveland Clinic · Updated on 2025-08-20

1200

Participants Needed

Research Sites

N/A

Total Duration

AI-Summary

What this Trial Is About

Researchers are studying the quality of life in adults with hypertrophic cardiomyopathy HCM, thoracic aortic dilatation TAD, and radiation-induced heart disease RIHD who are not suitable candidates for surgery. This observational study aims to understand how these heart conditions affect patients daily lives and well-being. The research seeks to identify risk factors linked to lower quality of life and changes over time to improve long-term management. Participants are adults diagnosed with HCM, TAD, or RIHD who are visiting the Cleveland Clinic for the first time for cardiac evaluation without prior or planned surgery. They will complete the Cardiac Quality of Life QOL Survey electronically at three points baseline, 3 months, and 9 months. The survey covers five areasglobal, physical, emotional, social, and spiritual healthand measures self-efficacy and resilience. During the study, participants will provide information through these surveys to help assess their health status across multiple domains. Researchers will compare results at 3 and 9 months to baseline to understand changes in quality of life and the impact of heritability and radiation-induced disease. The total participation time is about nine months, with ongoing monitoring through outpatient clinic visits and electronic questionnaires.

CONDITIONS

Brief Title

A Cardiac Disease Quality of Life Study

Who Can Participate

Age: 18Years - 70Years

All Genders

Eligibility Criteria

You may qualify if you...

Patients aged 18 to 70 years at the time of consent
Confirmed diagnosis of hypertrophic cardiomyopathy, thoracic aortic dilatation, and/or radiation-induced heart disease
Being seen for the first time at the Cleveland Clinic Main Campus for a comprehensive cardiac evaluation
Access to a phone, computer, or tablet with internet to complete follow-up questionnaires

You will not qualify if you...

Previous surgery or planned surgery within nine months for hypertrophic cardiomyopathy or thoracic aortic dilatation
Inability or unwillingness to comply with study requirements as judged by the investigator
Inability to provide informed consent

Research Team

Milind Desai, M. D.

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