Actively Recruiting
Cardiac Hemodynamics During Left Ventricular Assist
Led by Region Östergötland · Updated on 2023-11-02
35
Participants Needed
1
Research Sites
356 weeks
Total Duration
On this page
Sponsors
R
Region Östergötland
Lead Sponsor
L
Linkoeping University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this observational study is to exploratively investigate intracardiac geometry and hemodynamics in patients with ongoing HeartMate 3-therapy in the Swedish Southeast Healthcare region. The main question it aims to answer is: \- How do different flow levels in the HeartMate 3 left ventricular assist system influence intracardiac geometry and hemodynamics? Participating research subjects are called upon to undergo three followed photon-counting CT scans, as well as certain echocardiographic imaging, all in one session. The research subject's HeartMate device is connected to software that allows for variations in the pump's flow between these image collections. Analyzed variables includes three-dimensional geometry, CFD-computed parameters such as blood velocity, pressure, turbulence, and blood stasis. The variables are related with device settings and, alongside, selected echocardiographic measurements and patient details such as age, BMI, and diagnostic codes for both method validation and comprehensive perspective.
CONDITIONS
Official Title
Cardiac Hemodynamics During Left Ventricular Assist
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Connected to Linköping University Hospital in the Swedish Southeastern healthcare region
- Treatment with HeartMate 3 implanted more than 6 months ago
- Age over 18 years
You will not qualify if you...
- Reduced kidney function (eGFR below 45 ml/min/1.73m2)
- Known allergy to iodine contrast
- Untreated manifest hyperthyroidism
- Suspected or newly diagnosed thyroid cancer where radioiodine examination or treatment may be needed
- Diagnosis of Myasthenia Gravis
- Ongoing pregnancy
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Linköping University Hospital
Linköping, Östergötland County, Sweden, 58185
Actively Recruiting
Research Team
H
Hans Granfeldt, MD/PhD
CONTACT
L
Linus Ohlsson, PhD-student
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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