Actively Recruiting

Age: 0Years - 18Years
All Genders
NCT06898320

Cardiac Injury Due to Anthracycline in Paediatric Oncological Patients

Led by IRCCS Burlo Garofolo · Updated on 2025-05-09

22

Participants Needed

1

Research Sites

521 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The study investigates the role of echocardiography and of serum biomarkers (NT-proBNP, cardiac Troponin-I) in predicting cardiac injury in a cohort of paediatric oncological patients treated with Anthracycline chemotherapy.

CONDITIONS

Official Title

Cardiac Injury Due to Anthracycline in Paediatric Oncological Patients

Who Can Participate

Age: 0Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Pediatric oncological patients aged 0 to 18 years
  • Planned start of Anthracycline chemotherapy
  • Normal left ventricular systolic function according to International Guidelines before Anthracycline treatment
Not Eligible

You will not qualify if you...

  • Previous Anthracycline treatment, bone marrow transplantation, or chest radiation
  • Echocardiographic evidence before Anthracycline treatment of more than mild pericardial effusion
  • Echocardiographic evidence before Anthracycline treatment of more than mild mitral regurgitation
  • Poor echocardiographic acoustic window

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

IRCCS Burlo Garofolo

Trieste, Italy, Italy, 34137

Actively Recruiting

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Research Team

T

Thomas Caiffa, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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