Risk Stratification of Sudden Cardiac Death in Nonischemic Dilated Cardiomyopathy: Arrhythmogenic Substrate Assessment in Cardiac MRI.
Di Zhou, Huaying Zhang, Wenjing Yang...
https://pubmed.ncbi.nlm.nih.gov/40923889/Actively Recruiting
Led by Chinese Academy of Medical Sciences, Fuwai Hospital · Updated on 2022-10-31
2500
Participants Needed
1
Research Sites
52 weeks
Total Duration
Dilated cardiomyopathy DCM is a serious heart condition marked by weakened heart muscle and enlarged heart chambers, leading to risks such as sudden cardiac death or advanced heart failure. Researchers are studying the use of cardiac magnetic resonance CMR, a detailed imaging method that measures heart mass, volume, and function, to better assess risk and diagnose DCM. This observational study aims to understand how CMR can help in predicting outcomes for people with DCM over a long-term period. Participants will undergo cardiac magnetic resonance imaging to evaluate heart structure and function. The study does not involve experimental treatments but focuses on monitoring patients with DCM using CMR. The study will track outcomes such as all-cause mortality, sudden cardiac death, heart failure worsening, and major adverse cardiac events over a period of 1 to 10 years. During the study, participants will be followed up regularly to assess their health status and heart function using CMR and other clinical evaluations. Researchers will collect data on mortality and cardiac events to analyze risk factors linked to DCM. This long-term observation will help improve understanding of disease progression and potential risk stratification in patients with DCM.
CONDITIONS
Cardiac Magnetic Resonance for Risk Stratification in Dilated Cardiomyopathy
M
Minjie Lu, PhD
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Chinese Academy of Medical Sciences, Fuwai Hospital
Lead Sponsor
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo cardiac magnetic resonance to assess heart function and structure.
1 visit (in-person)
Duration - 1 to 10 years
Participants are observed for up to 10 years to track heart-related outcomes and overall health.
Periodic follow-up visits as determined by the study team
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Lead Sponsor