Cardiac MRI Study to Predict Outcomes in Non-dilated Left Ventricular Cardiomyopathy Using Heart Imaging for Risk Assessment and Better Treatment

What this Trial Is About

Researchers are examining non-dilated left ventricular cardiomyopathy NDLVC, a subtype of heart muscle disease characterized by abnormalities without enlargement of the left ventricle. This retrospective observational study aims to explore how cardiac magnetic resonance CMR findings relate to long-term outcomes and to identify key risk factors for serious heart-related events in patients with NDLVC. The purpose is to develop a CMR-based risk stratification method to help guide clinical decisions and improve patient care. Patients diagnosed with NDLVC who underwent CMR at the study institution during the specified period will be enrolled retrospectively. Key CMR parameters analyzed include left ventricular ejection fraction LVEF, late gadolinium enhancement LGE patterns, myocardial strain, and the extent of myocardial fibrosis or fatty replacement. The primary outcome measured is a combination of major adverse cardiac events, such as death, heart transplantation, or left ventricular assist device implantation. Participant data will be collected from medical records and CMR databases. The study will assess these imaging features against patient outcomes over a follow-up period of up to 100 months. By analyzing these factors, the research aims to clarify the link between specific CMR characteristics and prognosis in NDLVC. This will support better risk assessment and improve clinical management strategies for affected patients.

Cardiac Magnetic Resonance for Risk Stratification in Non-dilated Left Ventricular Cardiomyopathy