Actively Recruiting

Age: 18Years +
All Genders
NCT06566625

Cardiac MRI Prior to Invasive Coronary Angiography in Patients With Suspected Non-ST-Elevation Myocardial Infarction

Led by Region Stockholm · Updated on 2024-08-22

150

Participants Needed

1

Research Sites

71 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Patients with a suspected myocardial infarction are subdivided into ST-elevation and non-ST-elevation myocardial infarctions (STEMI and NSTEMI, respectively) using an ECG. While patients with STEMI are urgently referred to a cath lab, patients with NSTEMI usually undergo a planned invasive coronary angiography (ICA) anywhere from 24-72 hours after arriving to the hospital. When an invasive coronary angiography can not explain the cause of a myocardial infarction, an MRI of the heart (a CMR) is often done as a follow-up investigation. A growing body of evidence suggests that performing a CMR before the planned ICA can provide an accurate diagnosis and defer the need for an ICA in many of these patients with NSTEMI.

CONDITIONS

Official Title

Cardiac MRI Prior to Invasive Coronary Angiography in Patients With Suspected Non-ST-Elevation Myocardial Infarction

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years of age or older with suspected non-ST-elevation myocardial infarction (NSTEMI) showing signs of acute coronary syndrome and no ST-elevation on initial ECG
  • Planned invasive coronary angiography (ICA) where cardiac MRI can be done first without delaying the ICA
  • Able to provide written informed consent
Not Eligible

You will not qualify if you...

  • Contraindications to cardiac MRI with gadolinium contrast such as claustrophobia, eGFR below 30 ml/min/1.73m2, contrast allergy, or MRI-incompatible implants
  • Arrhythmias that prevent cardiac MRI examination
  • Previous coronary artery bypass graft surgery (CABG)
  • Hemodynamic instability
  • Myocardial infarction within 6 months before inclusion

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Karolinska University Hospital

Stockholm, Sweden, 171 64

Actively Recruiting

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Research Team

D

Daniel F Andersson, M.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Cardiac MRI Prior to Invasive Coronary Angiography in Patients With Suspected Non-ST-Elevation Myocardial Infarction | DecenTrialz