Representation of cardiovascular magnetic resonance in the AHA / ACC guidelines.
Florian von Knobelsdorff-Brenkenhoff, Guenter Pilz, Jeanette Schulz-Menger
https://pubmed.ncbi.nlm.nih.gov/28942735Actively Recruiting
Age: 0 - 80Years
All Genders
Healthy Volunteers
ID05346094
A Multicenter Investigation of Cardiac Normal Values of Morphology, Function and Tissue Characteristics by Magnetic Resonance Imaging
Led by Chinese Academy of Medical Sciences, Fuwai Hospital · Updated on 2023-01-04
938
Participants Needed
1
Research Sites
25 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are conducting a study to establish age- and sex-specific normal values for heart structure and function in healthy Chinese adults. This includes using advanced cardiovascular magnetic resonance (CMR) techniques like steady-state free precession and novel methods to assess myocardial strain and tissue characteristics. The study aims to fill the gap in existing reference standards for cardiovascular measurements specific to the Chinese population, supporting better diagnosis and prognosis of heart diseases. The study involves no treatment or intervention as it is observational. Participants undergo cardiovascular magnetic resonance imaging to measure traditional and novel heart parameters. Data collected will contribute to a comprehensive database of normal heart values for Chinese adults, enhancing the understanding of heart health and assisting future cardiovascular research. Participants will be healthy volunteers without cardiovascular conditions or risk factors. They will undergo imaging sessions and clinical assessments to provide detailed heart structure and function data. The study will monitor the normal values of left and right heart structures and functions, as well as novel CMR parameters, over five years. This information will help improve early identification and prognosis of cardiovascular diseases.
CONDITIONS
Brief Title
Cardiac Normal Values Assessed by Magnetic Resonance Imaging
Who Can Participate
Age: 0 - 80Years
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Subjects without cardiovascular disease, cardiovascular related symptoms and risk factors judged by combining clinical manifestations, non-invasive imaging and laboratory examination
You will not qualify if you...
- Subjects clinically screened or previously diagnosed with cardiovascular disease and risk factors
- Subjects with serious non-cardiovascular diseases
- Subjects with poor quality of magnetic resonance imaging
- Subjects refused to participate in the study
- Subjects with contraindications to MRI
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Diagnostic Evaluation
Duration - Single time point
Participants undergo cardiovascular magnetic resonance imaging to assess cardiac morphology, function, and tissue characteristics.
1 visit (in-person)
Long-term Monitoring
Duration - Up to 5 years
Participants' cardiac normal values are observed over time to establish reference standards.
Trial Site Locations
Total: 1 location
1
Fuwai Hospital
Beijing, Beijing Municipality, China, 100037
Actively Recruiting
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Research Team
M
Minjie Lu
B
Baiyan Zhuang
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Published Research Related To This Trial
Role of cardiovascular magnetic resonance in the guidelines of the European Society of Cardiology.
Florian von Knobelsdorff-Brenkenhoff, Jeanette Schulz-Menger
https://pubmed.ncbi.nlm.nih.gov/26800662CMR publications from China of the last more than 30 years.
Di Zhou, Jing Xu, Shihua Zhao...
https://pubmed.ncbi.nlm.nih.gov/32394180European Cardiovascular Magnetic Resonance (EuroCMR) registry--multi national results from 57 centers in 15 countries.
Oliver Bruder, Anja Wagner, Massimo Lombardi...
https://pubmed.ncbi.nlm.nih.gov/23331632Quality assessment of cardiovascular magnetic resonance in the setting of the European CMR registry: description and validation of standardized criteria.
Vincenzo Klinke, Stefano Muzzarelli, Nathalie Lauriers...
https://pubmed.ncbi.nlm.nih.gov/23787094Acute adverse reactions to gadolinium-based contrast agents in CMR: multicenter experience with 17,767 patients from the EuroCMR Registry.
Oliver Bruder, Steffen Schneider, Detlev Nothnagel...
https://pubmed.ncbi.nlm.nih.gov/22093267The global cardiovascular magnetic resonance registry (GCMR) of the society for cardiovascular magnetic resonance (SCMR): its goals, rationale, data infrastructure, and current developments.
Global Cardiovascular Magnetic Resonance Registry (GCMR) Investigators, Raymond Y Kwong, Steffen E Petersen...
https://pubmed.ncbi.nlm.nih.gov/28187739The current landscape of imaging recommendations in cardiovascular clinical guidelines: toward an imaging-guided precision medicine.
Antonio Esposito, Guglielmo Gallone, Anna Palmisano...
https://pubmed.ncbi.nlm.nih.gov/32964326