Actively Recruiting

Early Phase 1
Age: 18Years +
All Genders
NCT05700617

Cardiac Power Output in Cardiogenic Shock Patients

Led by University of Chicago · Updated on 2025-07-08

5

Participants Needed

1

Research Sites

151 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The main purpose of this study is to determine whether differences in myocardial reserve predict clinical outcomes for heart failure patients.

CONDITIONS

Official Title

Cardiac Power Output in Cardiogenic Shock Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Left ventricular ejection fraction (LVEF) 40% or less
  • Referred for right heart catheterization for evaluation for advanced heart failure therapies including LVAD, heart transplant, inotrope therapy, or counter-pulsation
  • Referred for right heart catheterization for accurate invasive hemodynamic assessment due to worsening clinical status
  • Referred for assessment of myocardial recovery for possible device removal or mechanical support removal
  • Referred for cardiac function and valve assessment before planned valve surgery for mitral regurgitation or aortic insufficiency
  • Estimated glomerular filtration rate (eGFR) of 30 ml/min/1.73 m2 or higher
  • Age 18 years or older
  • Intent for hospital admission based on right heart catheterization data
Not Eligible

You will not qualify if you...

  • Estimated glomerular filtration rate (eGFR) less than 30 ml/min/1.73 m2
  • Severe coronary artery disease not treated by revascularization
  • Current acute coronary syndrome
  • Age under 18 years
  • History of significant ventricular arrhythmia without an implantable cardioverter defibrillator (ICD)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The University of Chicago

Chicago, Illinois, United States, 60637

Actively Recruiting

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Research Team

D

David Onsager, MD

CONTACT

D

Daniel Rodgers

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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