Actively Recruiting
Cardiac Rehabilitation in Decompensated Heart Failure
Led by Beni-Suef University · Updated on 2026-04-15
135
Participants Needed
1
Research Sites
13 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Heart failure is a common clinical condition that often leads to reduced exercise tolerance, shortness of breath, and poor quality of life. Many patients with heart failure also develop weakness of the inspiratory muscles, which contributes to limited physical activity and worsening functional capacity. Inspiratory muscle training (IMT) has been suggested as a useful rehabilitation method to improve respiratory muscle strength and exercise tolerance. In addition, functional electrical stimulation (FES) of the lower limb muscles may help activate skeletal muscles and improve functional performance in patients who cannot tolerate conventional exercise. This randomized controlled study aims to investigate the effect of combining inspiratory muscle training with functional electrical stimulation of the lower limbs in patients with decompensated heart failure. A total of 135 hospitalized patients with decompensated heart failure will be recruited from the Cardiology Department at Beni-Suef University Hospital and randomly assigned into three groups. Group A (45 patients) will receive routine medical treatment in addition to inspiratory muscle training combined with functional electrical stimulation. Group B (45 patients) will receive routine medical treatment with inspiratory muscle training only. Group C (45 patients) will receive routine medical treatment alone. The intervention will start during hospitalization and will continue for four weeks. The study will evaluate the effects of these interventions on cardiac function, inspiratory muscle strength, and functional capacity as primary outcomes. Secondary outcomes will include dyspnea severity, quality of life, heart rate, oxygen saturation, hand grip strength, and maximum expiratory pressure. The findings of this study may help clarify the potential role of combining inspiratory muscle training with functional electrical stimulation as part of cardiac rehabilitation in patients with decompensated heart failure.
CONDITIONS
Official Title
Cardiac Rehabilitation in Decompensated Heart Failure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged from 45 to 65 years old
- Both sexes
- Hospitalized heart failure patients with ejection fraction < 40%
- Conscious and cooperative
- Able to participate in training actively
You will not qualify if you...
- Acute major cardiovascular events such as acute coronary syndrome, stroke, or pulmonary embolism
- Uncontrolled life-threatening arrhythmias
- Severe valvular heart disease requiring urgent surgery
- Pregnancy
- End-stage renal disease requiring dialysis
- Significant pulmonary diseases including pulmonary arterial hypertension
- Implanted pacemaker
- Clinically significant peripheral vascular disease
- Severe anemia
- Exercise-induced angina or ST-segment changes
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Beni-Suef University Hospital
Banī Suwayf, Beni-Suef Governorate, Egypt
Actively Recruiting
Research Team
S
Salma mostafa Elsalhy, BSc
CONTACT
M
MAHMOUD IBRAHIM MOHAMED, PT, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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