Actively Recruiting
Cardiometabolic Adaptations to Resistance and Endurance Exercise: Effects of Effort Configuration in Concurrent Training for Postmenopausal Women
Led by Universidade da Coruña · Updated on 2026-04-28
60
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
U
Universidade da Coruña
Lead Sponsor
M
Ministerio de Ciencia e Innovación, Spain
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are studying the effects of a 20-week concurrent training program combining endurance and resistance exercises on neuromuscular adaptations, body composition, cardiometabolic health, quality of life, mood, physical self-perception, and menopause-related symptoms in physically active postmenopausal women. This study aims to compare different combinations of endurance and resistance training with varying effort configurations to find the optimal program that maximizes health benefits. The research builds on previous findings by including controlled endurance training to better understand interactions between exercise types during menopause. Participants will follow a supervised concurrent training program with four sessions per week: two endurance and two resistance training sessions. Resistance exercises target major muscle groups using loads with 12-repetition maximum effort and specific rest periods to maintain consistent work-to-rest ratios. Endurance training consists of cycling exercises at prescribed intensities based on exercise testing, with session durations of thirty minutes. Different groups will perform variations of resistance training set configurations combined with moderate-intensity continuous cycling or aerobic interval training at low or high effort levels. Participants will be assessed at baseline and during partial evaluations at weeks 6, 12, 18, and after the 24-week intervention. Measurements include blood pressure, heart rate variability, arterial stiffness, metabolic rate, quality of life, menopause symptoms, mood, physical self-perception, blood lipid and glucose levels, oxidative stress markers, muscle strength, and fitness levels. Additional outcomes include body composition, bone density, muscle morphology, dietary habits, physical activity, and exercise responses. The study will monitor participants' progress and adaptations throughout the program to understand the long-term effects of concurrent training on postmenopausal women's health.
CONDITIONS
Brief Title
Cardiometabolic Adaptations to Concurrent Training: Effect of Effort Configuration on Postmenopausal Women
Who Can Participate
Eligibility Criteria
You may qualify if you...
- At least one year since the last menstrual period
- Physically active, with 150-300 minutes of moderate or at least 75 minutes of vigorous activity weekly
- Three or fewer traditional cardiovascular risk factors
- Asymptomatic without cardiovascular (except controlled hypertension), metabolic, or renal diseases
- Well-controlled grade 1 hypertension managed with a single medication (if hypertensive)
You will not qualify if you...
- Diagnosis of grade 2 or grade 3 hypertension
- Hypertension managed with more than one medication or drugs that affect cardiovascular exercise responses (e.g., beta-blockers)
- Current or previous use of hormone replacement therapy
- Hypertensive response to exercise
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 20 weeks
Participants engage in a 20-week concurrent training program consisting of four supervised training sessions per week, including two endurance sessions and two resistance training sessions targeting major muscle groups. Each session lasts approximately 30 minutes with specific work-to-rest ratios maintained.
Four training sessions per week (in-person)
Duration - Up to 24 weeks from baseline
Periodic assessments occur throughout the 24-week study period to monitor cardiometabolic and neuromuscular adaptations, including evaluations at baseline, weeks 6, 12, 18, and post-intervention at week 24.
Assessments at 5 timepoints: baseline, week 6, week 12, week 18, and week 24
Trial Site Locations
Total: 1 location
1
Faculty of Sport Sciences and Physical Education - UDC
Oleiros, A Coruña, Spain, 1517
Actively Recruiting
Research Team
E
Eliseo Iglesias-Soler, PhD
M
María Rúa-Alonso, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
6
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