Actively Recruiting
CArdioMEtabolic Function and Reserve Capacity in Healthy Adults: The CAMERA Study
Led by Mayo Clinic · Updated on 2026-03-05
80
Participants Needed
1
Research Sites
153 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to evaluate pulmonary capillary wedge pressure (PCWP) and other hemodynamic measurements at rest and during exercise in healthy volunteers across the age spectrum.
CONDITIONS
Official Title
CArdioMEtabolic Function and Reserve Capacity in Healthy Adults: The CAMERA Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Apparently healthy volunteers without symptoms of breathlessness or fatigue
- No diagnosis of heart failure
- Left ventricular ejection fraction (EF) of 50% or higher
- Able and willing to undergo invasive hemodynamic exercise testing, MRI, and other study assessments
- Provided informed consent
You will not qualify if you...
- Clinically significant symptoms of breathlessness or fatigue in daily life
- Any diagnosis of heart failure
- Symptomatic coronary artery disease (such as chronic angina)
- Symptomatic valvular heart disease
- Pulmonary hypertension
- Cardiomyopathies
- High output heart failure
- Pericardial disease
- Clinically significant chronic lung disease
- Anemia (hemoglobin less than 12 gm/dL in women and less than 13 gm/dL in men)
- Estimated glomerular filtration rate 30 mL/min or lower
- Pregnant women
- Any other disorders that would interfere with safe participation (e.g., psychiatric disorder or substance abuse)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mayo Clinic in Rochester
Rochester, Minnesota, United States, 55905
Actively Recruiting
Research Team
A
Alyssa Ploof
CONTACT
B
Barry Borlaug, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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