Actively Recruiting

Age: 18Years +
All Genders
NCT07529145

Cardiopulmonary Exercise Testing in Lung Cancer Patients Before and During Oncological Treatment

Led by Medical University of Bialystok · Updated on 2026-04-14

90

Participants Needed

1

Research Sites

86 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Patients with lung cancer often have reduced physical fitness and coexisting health problems, which may limit their ability to tolerate oncological treatment. Standard resting lung and heart tests do not always reflect real-life physical capacity during everyday activities or physical effort. This observational study aims to assess cardiorespiratory fitness in patients with lung cancer before and during standard oncological treatment using cardiopulmonary exercise testing (CPET). CPET is a safe, supervised exercise test that provides objective information on how the heart, lungs, and muscles respond to physical effort. Participants with WHO/ECOG performance status 0-2 will undergo CPET before treatment initiation and again after the early phase of therapy or surgery. The results may help identify patients with reduced physiological reserve and support individualized monitoring during routine clinical care.

CONDITIONS

Official Title

Cardiopulmonary Exercise Testing in Lung Cancer Patients Before and During Oncological Treatment

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age ≥ 18 years
  • Histologically confirmed lung cancer (any stage)
  • Qualified for standard oncological management (surgery and/or systemic therapy)
  • WHO/ECOG performance status 0-2
  • Ability to perform cardiopulmonary exercise testing (CPET)
  • Written informed consent
Not Eligible

You will not qualify if you...

  • Unstable ischemic heart disease
  • Symptomatic cardiac arrhythmias
  • Myocarditis or pericarditis
  • Decompensated heart failure
  • Active deep vein thrombosis
  • Suspected aortic dissection or severe aortic stenosis
  • Poorly controlled asthma
  • Resting oxygen saturation ≤ 85% on room air
  • Clinically relevant treatment-related adverse events above mild intensity (as applicable)
  • Any medical condition that, in the investigator's opinion, precludes safe participation in CPET
  • Withdrawal of informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Clinical Hospital in Bialystok, II Department of Pulmonology, Lung Cancer and Internal Medicine, Medical University of Bialystok

Bialystok, Podlaskie Voivodeship, Poland, 15-276

Actively Recruiting

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Research Team

K

Klaudia Jadczak, Medical Doctor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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