Actively Recruiting
Cardiotoxicity Assessment Through Comprehensive Heart Imaging to Predict Heart Failure
Led by Hari Narayan · Updated on 2025-01-28
150
Participants Needed
1
Research Sites
574 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Anthracycline chemotherapies (e.g. doxorubicin, daunorubicin) are commonly given to treat pediatric cancer, and carry a risk of cardiotoxicity. Over the long term, children who receive these therapies have an increased risk of heart failure and early cardiovascular death. However, current strategies for identifying patients who are at risk prior to the development of significant changes in heart function are limited. This study will focus on imaging markers of cardiac injury and dysfunction with the goal of developing improved diagnostic tests and treatment strategies.
CONDITIONS
Official Title
Cardiotoxicity Assessment Through Comprehensive Heart Imaging to Predict Heart Failure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- English and Spanish speaking male and female subjects, ages 13-39 years old
- Diagnosis of cancer at age <22 years
- Previously treated with anthracycline therapy for cancer, with diagnosis at least two years prior.
You will not qualify if you...
- Contraindication to cardiac MRI, including non-MRI compatible metallic implants
- Medical, psychiatric, or social disorders preventing completion of study testing or cardiac MRI without anesthesia
- History of congenital heart disease more significant than patent foramen ovale or patent ductus arteriosus
- Pregnancy at the time of enrollment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Rady Children's Hospital
San Diego, California, United States, 92123
Actively Recruiting
Research Team
H
Hari Narayan, MD
CONTACT
C
Cesar Vasquez
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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