Actively Recruiting
Cardiovascular Function and Response to Stimulation Within the First Year After Spinal Cord Injury
Led by Kessler Foundation · Updated on 2025-09-05
5
Participants Needed
1
Research Sites
82 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study aims to explore how cardiovascular function changes in the first year after a spinal cord injury, and to see how different treatments, like spinal stimulation through the skin (transcutaneous spinal stimulation), affect blood pressure. The main questions are: How does stimulation affect blood pressure over the year? What is the level of cardiovascular activation throughout the year? The study will start during the inpatient stay at the Kessler Institute for Rehabilitation and continue after discharge as an outpatient, totaling about 20-29 sessions over the year.
CONDITIONS
Official Title
Cardiovascular Function and Response to Stimulation Within the First Year After Spinal Cord Injury
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Individuals with a spinal cord injury undergoing inpatient rehabilitation at the Kessler Institute for Rehabilitation
- Between 18 and 75 years old
- Injury occurred 7 to 50 days before the study
- Injury level at or above T6 (cervical or high chest injury)
- Experiencing low blood pressure after injury
- Classified as American Spinal Injury Association Impairment Scale (AIS) A or B
You will not qualify if you...
- Currently require a ventilator for breathing
- Have implanted devices such as brain/spine/nerve stimulators, cardiac pacemaker/defibrillator, or intra-cardiac lines
- Have significant vascular or heart conduction diseases or recent heart attack
- Started new medication for blood pressure or heart problems within the last five days (excluding midodrine)
- Have a known infection or current illness that may interfere with the study (e.g., urinary tract infection, deep vein thrombosis, blood clotting issues, pressure injury)
- Have a history of seizures
- Are pregnant
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Kessler Foundation
West Orange, New Jersey, United States, 07052
Actively Recruiting
Research Team
L
Leighann Martinez, BA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here