Actively Recruiting
Cardiovascular Risk in Children With Chronic Conditions Study
Led by Semmelweis University · Updated on 2025-08-08
300
Participants Needed
3
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Children with chronic health conditions have a higher chance of developing heart and blood vessel diseases earlier than their peers due to faster aging of these organs. Experts recommend careful monitoring and early care, but the exact causes of this increased risk are not well understood. This research seeks to better understand why these children face greater cardiovascular risks and to support future prevention efforts. The study observes children and young adults aged 6 to 25 who have chronic conditions linked to higher cardiovascular risk. It uses non-invasive methods to check the health of large blood vessels like the carotid artery and small vessels in the retina. These assessments include measuring arterial stiffness, endothelial function of the brachial artery, and retinal vessel features, all done at the start and during yearly follow-ups. Participants will undergo regular evaluations including scans of blood vessels and retinal imaging to monitor changes over time. The study measures key indicators such as arterial stiffness and retinal vessel diameter to track early signs of vascular aging. This ongoing observation helps researchers identify those at risk before obvious heart or vascular disease appears. The study is sponsored by Semmelweis University and runs until 2029, involving close monitoring without intervention.
CONDITIONS
Brief Title
Cardiovascular Risk in Children With Chronic Conditions Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Individuals aged between 6 and 25 years
- Diagnosed with a chronic childhood condition or disease linked to increased cardiovascular risk
- Provided informed consent or had consent from a legal guardian if under 18
- Chronic conditions defined by American Heart Association 2019 recommendations or supported by at least two large studies
You will not qualify if you...
- Severe intellectual and developmental disability
- Decompensated heart failure
- Severe primary immunodeficiency
- Ongoing intravenous chemotherapy
- Infectious diseases posing public health risk
- History of regular alcohol or drug use
Research Team
T
Tamas Kiss, MD, PhD
B
Bálint Mikes, MD, PhD
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