Actively Recruiting
Led by Semmelweis University · Updated on 2025-08-08
300
Participants Needed
3
Research Sites
N/A
Total Duration
Children with chronic health conditions have a higher chance of developing heart and blood vessel diseases earlier than their peers due to faster aging of these organs. Experts recommend careful monitoring and early care, but the exact causes of this increased risk are not well understood. This research seeks to better understand why these children face greater cardiovascular risks and to support future prevention efforts. The study observes children and young adults aged 6 to 25 who have chronic conditions linked to higher cardiovascular risk. It uses non-invasive methods to check the health of large blood vessels like the carotid artery and small vessels in the retina. These assessments include measuring arterial stiffness, endothelial function of the brachial artery, and retinal vessel features, all done at the start and during yearly follow-ups. Participants will undergo regular evaluations including scans of blood vessels and retinal imaging to monitor changes over time. The study measures key indicators such as arterial stiffness and retinal vessel diameter to track early signs of vascular aging. This ongoing observation helps researchers identify those at risk before obvious heart or vascular disease appears. The study is sponsored by Semmelweis University and runs until 2029, involving close monitoring without intervention.
CONDITIONS
Cardiovascular Risk in Children With Chronic Conditions Study
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 1 day
Participants undergo baseline assessments of cardiovascular health including arterial stiffness, endothelial function, and retinal vessel measurements.
1 baseline visit (in-person)
Duration - Up to 7 years
Participants are followed annually to repeat cardiovascular assessments and monitor changes over time.
Annual visits for up to 7 years
Total: 3 locations
1
Semmelweis University, Department of Surgery, Transplantation and Gastroenterology
Budapest, Hungary, 1082
Not Yet Recruiting
2
Semmelweis University, Pediatric Center
Budapest, Hungary, 1083
Actively Recruiting
3
Semmelweis University, Institute of Preventive Medicine and Public Health
Budapest, Hungary, 1089
Active, Not Recruiting
T
Tamas Kiss, MD, PhD
B
Bálint Mikes, MD, PhD
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Have more questions? Get in touch with our team for quick support
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Henner Hanssen, Trine Moholdt, Martin Bahls...
https://pubmed.ncbi.nlm.nih.gov/37491406Benjamin J Varley, Reeja F Nasir, Michael R Skilton...
https://pubmed.ncbi.nlm.nih.gov/36029824Olli Raitakari, Katja Pahkala, Costan G Magnussen
https://pubmed.ncbi.nlm.nih.gov/34987194Sarah D de Ferranti, Julia Steinberger, Rebecca Ameduri...
https://pubmed.ncbi.nlm.nih.gov/30798614David R Jacobs, Jessica G Woo, Alan R Sinaiko...
https://pubmed.ncbi.nlm.nih.gov/35373933Nick Townsend, Denis Kazakiewicz, F Lucy Wright...
https://pubmed.ncbi.nlm.nih.gov/34497402