Study Comparing Cardiovascular Risk in Adults with Digital Osteoarthritis and Those with Other Non-Arthritic Conditions

What this Trial Is About

Researchers are investigating cardiovascular risk in people with digital osteoarthritis by comparing them to patients with non-osteoarthritis conditions. This cross-sectional case-control study measures carotid intima-media thickness to assess differences in cardiovascular risk between these groups. The study also involves clinical assessments with rheumatologists and evaluates cardiovascular health more broadly. Participants will undergo several procedures including an ultrasound scan to measure carotid intima-media thickness, a hand ultrasound to assess joint condition, and use of the EndoPAT 2000 system to detect coronary artery endothelial dysfunction. Bone mineral density and body composition will be measured by DXA scanning, and physical performance will be evaluated by a 6-minute walking test. These assessments help compare cardiovascular risk factors and joint health between the digital osteoarthritis group and control patients with spine or osteoporosis conditions. During the study, participants will have clinical evaluations by rheumatologists, various imaging and functional tests, and cardiovascular risk assessments using the SCORE scale. The main outcome is carotid intima-media thickness measured in about 20 minutes, alongside secondary measures including cardiovascular risk scores, endothelial function, bone density, and walking ability. The total participation involves these assessments to better understand cardiovascular risk in digital osteoarthritis. The study is sponsored by University Hospital, Clermont-Ferrand and runs until October 2026.

Cardiovascular Risk in Digital Osteoarthritis