Study of Cardiovascular Risk Factors and Dietary Effects in Adults with Coeliac Disease

What this Trial Is About

Researchers are investigating the key cardiovascular risk factors, including metabolic parameters and body composition, in people with coeliac disease CD. This research focuses on newly diagnosed and treated CD patients to understand how these factors change over time, especially during a gluten-free diet GFD. The study also evaluates whether a structured dietary intervention can reduce negative effects associated with an unbalanced diet in these patients. The study includes a randomized controlled trial where participants are assigned either to a dietary intervention group receiving structured, group-based online dietary counseling focused on maintaining a GFD and adopting a Mediterranean diet, or to a standard care group receiving baseline dietary education. The counseling consists of six sessions over one year, with monthly meetings for five months and a final session at month nine. The study also collects detailed data on body composition and cardiovascular risk markers. Participants will undergo various assessments including body composition measurement, questionnaires on symptoms, quality of life, and diet adherence, blood tests for metabolic and immunological parameters, urine tests for gluten intake, and ultrasound scans to check for fatty liver disease. These evaluations occur over one year to monitor changes in percent body fat and other health markers. The study aims to improve understanding of metabolic and cardiovascular health in CD and to optimize follow-up care.

Cardiovascular Risk Factors in Coeliac Disease: a Series of Studies