Actively Recruiting
Care of the Prostate Cancer Patient and Prospective Procurement of Prostate Cancer Tissue
Led by National Cancer Institute (NCI) · Updated on 2026-05-14
3000
Participants Needed
1
Research Sites
1097 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Background: Prostate cancer is the most common noncutaneous cancer among men in the U.S. Researchers want to study blood, tissue, and fluid samples of people with prostate cancer. This will help them understand any changes in cells and genes. These changes might lead to the development and progression of prostate cancer. Researchers think the study could lead to new treatments. Objective: To understand the changes in cells and genes that lead to the development and progression of prostate cancer. This could lead to new treatments. Eligibility: Men ages 18 and older who have or are suspected to have prostate cancer Design: Participants will be screened with physical exam and medical history. Participants will send tissue blocks of their tumor, if possible. If not, they will provide unstained slides of tumor tissue. Participants may provide samples of blood, urine, saliva, and prostate secretions. Participants may have imaging tests. They will lie in a machine that takes pictures of their body. These tests include: MRI of the prostate CT of the abdomen and pelvis Chest x-ray Participants may need a biopsy or surgery for treatment of their cancer. If so, researchers will collect tissue. Participants may answer questions about their prostate cancer and quality of life. Participants may have follow-up visits or other treatments. They may have follow-up phone calls every few months.
CONDITIONS
Official Title
Care of the Prostate Cancer Patient and Prospective Procurement of Prostate Cancer Tissue
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults 18 years or older with biopsy-proven or suspected prostate cancer
- Require and willing to undergo diagnostic or therapeutic intervention as part of diagnosis, standard care, or follow-up
- ECOG performance status of 0 to 2
- Able and willing to provide informed consent
- PSA greater than or equal to 1.0 ng/ml for patients aged 30 to 49 years
- PSA greater than or equal to 2.5 ng/ml for patients 50 years or older
- Abnormal digital rectal exam (enlarged, asymmetric, nodular, firm, or tender prostate)
- Abnormal prostate MRI finding
- Family history of prostate cancer in brother or father, or breast or ovarian cancer in mother or sister
You will not qualify if you...
- Medical conditions that prevent diagnostic or therapeutic intervention
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892
Actively Recruiting
Research Team
K
Karen K Holcomb
CONTACT
P
Peter A Pinto, M.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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