Actively Recruiting

Phase Not Applicable
Age: 21Years +
All Genders
Healthy Volunteers
NCT06152081

Caries Detection With Two Different Caries Detecting Devices

Led by Tufts University · Updated on 2025-08-05

60

Participants Needed

1

Research Sites

130 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The primary aim of this study will be to compare the effectiveness of the novel LumiCare™ rinse and with QLF in determining caries progression. The secondary aim is to compare the progression of carious lesions between patients who reported use of e-cigarettes/vapes and those who did not.

CONDITIONS

Official Title

Caries Detection With Two Different Caries Detecting Devices

Who Can Participate

Age: 21Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients of TUSDM Comprehensive Care Clinic
  • Adults 21 years or older
  • Classified as extreme or high caries risk per TUSDM CAMBRA form
  • Have 2 or more initial active primary carious lesions on free coronal tooth surfaces detected by visual assessment, QLF, and LumiCare™
  • Have at least 1 cavitated lesion
  • Have updated bite wing radiographs no older than 6 months
  • Have responded yes or no to use of e-cigarettes or vapes
  • Have at least 1 active caries, 1 inactive caries, and 1 sound tooth surface
Not Eligible

You will not qualify if you...

  • Classified as low or moderate caries risk per TUSDM CAMBRA form
  • No clinically detectable carious lesions on free coronal surfaces
  • No cavitated caries lesions
  • Carious teeth with lesions alongside extrinsic stains, fluorosis, or developmental defects
  • Use of conventional cigarettes or smokeless tobacco

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Tufts University School of Dental Medicine

Boston, Massachusetts, United States, 02111

Actively Recruiting

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Research Team

K

Karina Irusa, BDS,MS

CONTACT

A

Ann-Marie Billig

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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