Actively Recruiting
Carnosine for Peripheral Arterial Disease Patients
Led by Shahid Baba · Updated on 2024-07-22
20
Participants Needed
1
Research Sites
95 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Oral supplementation of L-carnosine will increase muscle carnosine, stabilize HIF1-alpha promote angiogenesis, and thus improve the functioning of lower extremities in PAD patients.
CONDITIONS
Official Title
Carnosine for Peripheral Arterial Disease Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male subjects older than 50 and younger than 80 years of age
- White or African American race
- English speaking
- Ankle-brachial index (ABI) between 0.4 and less than 0.60
- Willing to comply with study requirements
- Able to provide informed consent
You will not qualify if you...
- Having HIV, hepatitis, significant liver disease, active infection, anemia, organ transplant, kidney disease requiring dialysis, lung disease needing oxygen, significant congenital heart disease, any cancer, or untreated thyroid disease
- Diagnosis of carnosinemia
- Known allergy to L-carnosine or meat
- Presence of a pacemaker
- Obesity caused by a known genetic defect
- Dementia
- Critical limb ischemia with below or above knee amputations
- Foot ulcers
- Major amputations
- Participating in other clinical trials
- End-stage renal disease
- Significant injury within 30 days before enrollment
- Prisoner status
- Any metallic implants
- Poorly controlled diabetes with HbA1C greater than 9%
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Louisville
Louisville, Kentucky, United States, 40202
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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