Actively Recruiting

Phase Not Applicable
Age: 45Years - 80Years
All Genders
NCT05257161

Carotid Revascularization With MicroNet Covered Stent Comparing Early Neurological Outcomes With Distal Versus Proximal EPS

Led by Meshalkin Research Institute of Pathology of Circulation · Updated on 2022-02-25

366

Participants Needed

1

Research Sites

269 weeks

Total Duration

On this page

Sponsors

M

Meshalkin Research Institute of Pathology of Circulation

Lead Sponsor

F

Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health

Collaborating Sponsor

AI-Summary

What this Trial Is About

The SIBERIA study demonstrated a clear advantage of CGuard stent implantation over the existing classical stent when using a distal anti-embolic device. At the same time, there is no Level 1 evidence for a difference between the proximal and distal anti-embolic device for the CGuard stent.

CONDITIONS

Official Title

Carotid Revascularization With MicroNet Covered Stent Comparing Early Neurological Outcomes With Distal Versus Proximal EPS

Who Can Participate

Age: 45Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 45 and 80 years
  • Accepted for carotid artery stenting after neurological consultation and qualification
  • Life expectancy longer than 6 months
  • Suitable clinical condition for diffusion-weighted MRI
  • Provided written informed consent approved by Ethics Committee
  • Agrees to complete all required follow-up procedures and visits
Not Eligible

You will not qualify if you...

  • Enrolled in another investigational device or drug study that is not completed or interferes with this study
  • Recent surgery within 30 days before or planned surgery within 30 days after stenting
  • Active liver disease (bilirubin > 35 mmol/l) or kidney insufficiency (creatinine > 2.5 mg/dL or glomerular filtration rate < 60 ml/min)
  • Recent evolving acute stroke within 30 days prior to evaluation
  • Myocardial infarction within 72 hours before stenting (CPK-MB > 3 times normal)
  • Female patients of childbearing potential or known pregnancy
  • Known stroke causes other than carotid stenosis, such as atrial fibrillation, atrial flutter, or thrombophilia
  • Patient taking vitamin K antagonists or new oral anticoagulants

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

E. Meshalkin National Medical Research Center

Novosibirsk, Russia

Actively Recruiting

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Research Team

A

Andrey A Kaprenko, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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