Actively Recruiting

Phase 2
Phase 3
Age: 18Years +
All Genders
NCT04499898

Carvedilol Versus Endoscopic Band Ligation for Primary Prophylaxis of Oesophageal Variceal Bleeding

Led by Sherief Abd-Elsalam · Updated on 2020-08-05

306

Participants Needed

1

Research Sites

636 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Carvedilol versus endoscopic band ligation for primary prophylaxis of oesophageal variceal bleeding in cirrhotic patients with arterial hypertension

CONDITIONS

Official Title

Carvedilol Versus Endoscopic Band Ligation for Primary Prophylaxis of Oesophageal Variceal Bleeding

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged >18 years
  • Cirrhotic patients with arterial hypertension
  • Endoscopic evidence of medium/large-sized esophageal varices
Not Eligible

You will not qualify if you...

  • History of variceal bleeding or previous primary prevention of varices
  • Portal vein thrombosis or previous porto-systemic shunts such as TIPS
  • Use of drugs affecting portal pressure (beta blockers, nitrates)
  • Advanced cardiovascular disease including acute myocardial infarction, atrio-ventricular block, congestive heart failure, chronic peripheral ischemia, severe bradycardia
  • Severe respiratory diseases such as COPD or bronchial asthma
  • Uncontrolled diabetes mellitus
  • Renal impairment
  • Hepatocellular carcinoma
  • Allergy to carvedilol
  • Pregnancy or lactation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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2
3
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Trial Site Locations

Total: 1 location

1

Sherief Abd-Elsalam

Tanta, Egypt

Actively Recruiting

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Research Team

S

Sherief Abd-Elsalam, ass. prof.

CONTACT

N

Nabila el-gazzar, ass. lect.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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Carvedilol Versus Endoscopic Band Ligation for Primary Prophylaxis of Oesophageal Variceal Bleeding | DecenTrialz